124 citations
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January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
24 citations
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July 2021 in “Pharmaceutics” Ruxolitinib cream effectively targets and treats inflammatory skin diseases.
December 2013 in “Estudo Geral (Universidade de Coimbra)” Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
March 2012 in “Reactions Weekly” A man had a rare skin reaction from a hair loss medication, which improved after stopping the drug.
5-ARI therapy may help prevent prostate cancer progression.
March 2005 in “Journal of The American Academy of Dermatology” Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.
December 2020 in “Forum Dermatologicum” Intralesional triamcinolone acetonide can effectively limit the progression of GLPLS.
1 citations
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April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Oral tofacitinib significantly improves lichen planopilaris symptoms without adverse effects.
20 citations
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June 2019 in “JAAD Case Reports” Tofacitinib can cause skin eruptions similar to palmoplantar pustulosis.
8 citations
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August 2022 in “Microorganisms” The document discussed the challenges and lessons learned from repurposing drugs for COVID-19 treatment, emphasizing the need for a standardized translational drug development platform. It highlighted the importance of a systematic approach to drug repurposing, which was crucial during the pandemic to quickly identify potential treatments. The study involved various experimental conditions and pharmacokinetic studies, particularly using Syrian golden hamsters as models. Key findings included the high potency of molnupiravir and nirmatrelvir in vitro, while other drugs like atazanavir and favipiravir showed limited efficacy. The research underscored the potential of certain drug combinations and the need for ongoing evaluation of new candidates based on emerging data. The authors concluded that a standardized platform could enhance the efficiency and effectiveness of drug development, especially in urgent situations like a pandemic.
September 2025 in “International Journal of Pharmacy and Biomedical Engineering” Drug repurposing finds new uses for existing drugs, speeding up treatment availability and reducing costs.
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September 2019 in “International Journal of Nanomedicine” RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
33 citations
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January 1979 in “Acta obstetricia et gynecologica Scandinavica” Diane® is an effective contraceptive that also helps treat acne and mild hair growth issues.
April 2023 in “Medicina Clínica (english Edition)”
May 2017 in “Journal of The American Academy of Dermatology” An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
February 2023 in “Research Square (Research Square)” Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
2 citations
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April 2023 in “Expert Review of Clinical Immunology” Baricitinib is effective as a treatment for severe hair loss.
9 citations
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April 2016 in “Australasian journal of dermatology” Combining imiquimod with diphenylcyclopropenone may improve treatment outcomes for alopecia areata patients who don't respond to diphenylcyclopropenone alone.
August 2018 in “Journal of The American Academy of Dermatology” A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.
3 citations
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August 2024 in “Cureus” Upadacitinib may cause hair loss.
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January 2015 in “Case reports in medicine” A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.
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July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
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March 2008 in “Neuropsychopharmacology”
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May 2023 in “Clinical drug investigation” JAK inhibitors for alopecia areata are linked to minor side effects like headache and acne, but not to an increased risk of serious adverse events.
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September 2017 in “Dermatologic surgery” The combination therapy improved skin pigmentation.
January 2026 in “Andrology” PRP injections are safe but don't significantly improve Peyronie's Disease.
June 2025 in “Experimental and Сlinical Urology” Predstanormix Duo is a safe and effective new drug for treating urinary symptoms from BPH.
March 2018 in “Suez Canal University Medical Journal” New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.