September 1988 in “Inpharma (Balgowlah)” Retinoids are effective for acne but can cause serious side effects.
Depo-Provera effectively prevents pregnancy but has many side effects and safety concerns, leading to its ban in the U.S.
November 2025 in “International Journal Of Ayurvedic And Herbal Medicine” A multidisciplinary approach effectively improves trichotillomania without side effects.
June 2025 in “Revista Foco” JAK inhibitors effectively treat severe alopecia areata with manageable side effects.
December 2024 in “Journal of General-Procedural Dermatology & Venereology Indonesia” The serum effectively reduces hair loss and improves hair growth without side effects.
November 2024 in “Journal of Cosmetic Dermatology” Baricitinib is effective for severe alopecia areata but has some side effects.
November 2023 in “Journal of Pakistan Society of Internal Medicine.” Methotrexate is effective for rheumatoid arthritis but can cause side effects.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Topical finasteride effectively treats hair loss and acne with fewer side effects than oral forms.
January 2012 in “International Society of Hair Restoration Surgery” Finasteride is effective for hair loss but has controversial side effects.
April 2011 in “The Journal of Urology” Finasteride effectively reduced priapism episodes in children with sickle cell disease without side effects.
March 2023 in “Clinical, Cosmetic and Investigational Dermatology” Spironolactone can effectively treat hair loss with manageable side effects.
September 2022 in “Journal of Cosmetic Dermatology” Oral minoxidil effectively treats different types of hair loss with fewer side effects.
278 citations
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May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
169 citations
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September 2002 in “British journal of dermatology/British journal of dermatology, Supplement” ZD1839 (Iressa) causes skin and hair side effects, treatable with tretinoin cream and minocycline.
117 citations
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August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
108 citations
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November 1980 in “British Journal of Dermatology” Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
94 citations
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January 2000 in “The Journal of Clinical Endocrinology and Metabolism” Spironolactone most effective for hirsutism, but has side effects.
86 citations
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September 1977 in “BMJ” Minoxidil effectively controls blood pressure in severe cases, but has serious side effects and causes hair growth in women.
82 citations
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March 1994 in “Archives of Dermatology” 2% topical minoxidil effectively treats female hair loss with minimal side effects.
81 citations
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February 2000 in “Anti-cancer drugs” Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
80 citations
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January 1995 in “The Nephron journals/Nephron journals” The treatment was effective for lupus nephritis with manageable side effects.
78 citations
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December 2008 in “The Journal of Sexual Medicine” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.
73 citations
,
January 1980 in “Annals of Neurology” Valproic acid can cause serious side effects, including pancreatitis and even death.
71 citations
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August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
57 citations
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January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
54 citations
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March 1987 in “Journal of The American Academy of Dermatology” 3% topical minoxidil effectively treats extensive alopecia areata with few side effects.
50 citations
,
May 2000 in “Fertility and Sterility” Flutamide reduces hair growth better but has more side effects.
49 citations
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November 2016 in “Frontiers in Pharmacology” Tripterygium wilfordii Hook F often causes side effects like stomach issues and skin reactions.
47 citations
,
June 2015 in “Medicines” Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.
44 citations
,
April 2011 in “Critical reviews in analytical chemistry” Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.