research The hair cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
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research Dermatoses of pregnancy
Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research The hair cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Eph/ephrin signaling in epidermal differentiation and disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Developing stratified epithelia: lessons from the epidermis and thymus
The skin and thymus develop similarly to protect and support immunity.
research Epidermal keratinocyte stem cells: their maintenance and regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Stem Cells behind the Barrier
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)
Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
research Epidermal stem cell fate: what can we learn from embryonic stem cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
research Equine Hoof Stem Progenitor Cells (HPC) CD29 + /Nestin + /K15 + – a Novel Dermal/epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment
Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
research Tumid Lupus Erythematosus and Systemic Lupus Erythematosus: A Report on Their Rare Coexistence
A woman with both TLE and SLE improved with hydroxychloroquine treatment.
research Human Pilosebaceous Culture
Hair follicle cells can help heal wounds and study skin diseases.
research Secondary Cicatricial Scalp Alopecia Caused by Brunsting-Perry Pemphigoid: A Case Report
Brunsting-Perry pemphigoid can cause scarring hair loss and may be underdiagnosed.
research Dermatomyositis Disease in Dogs
Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.
research Pathogenesis and clinical features of alopecia in epidermolysis bullosa: A systematic review
Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research 1465 Optimization/characterization of a Focal Dermal Hypoplasia mouse model to test potential treatments
Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
research Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research Calcium regulation of stem cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Commentary: Unroofing for hidradenitis suppurativa, why and how
Unroofing is an effective, less invasive, and cost-effective surgery for hidradenitis suppurativa with low recurrence and improved patient quality of life.
research Dermatopathology and molecular genetics
Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.
research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species
CD90 is present on specific cells in dog hair follicles.
research Cutaneous Markers of Disorders Affecting Adult Horses
Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.
research Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.