January 2026 in “British Journal of Dermatology” Staphylococcus aureus affects immune responses and skin cells in atopic dermatitis, suggesting new treatment targets.
Stem cell treatments show promise for improving skin and hair, but need more research and standardization.
August 2024 in “Indian Journal of Skin Allergy” Stem-cell therapy shows promise for skin conditions but needs more research.
January 2024 in “Journal of tissue engineering” Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
February 2022 in “Journal of Investigative Dermatology” Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
January 2016 in “mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)” A new test using NOS2 and CCL27 genes can better diagnose and treat psoriasis and eczema.
518 citations
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November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
351 citations
,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
205 citations
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July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
132 citations
,
April 2005 in “Gastroenterology” A gluten-free diet significantly improves skin and health issues in people with dermatitis herpetiformis, a skin condition linked to celiac disease.
131 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
127 citations
,
November 2010 in “Pigment cell & melanoma research” We need more research on human hair follicle pigmentation, not just mouse models.
125 citations
,
February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
118 citations
,
January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
116 citations
,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
114 citations
,
August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
106 citations
,
August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
100 citations
,
May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
90 citations
,
July 2020 in “Stem Cell Research & Therapy” Stem cell vesicles can reduce skin aging from UVB by lowering inflammation and oxidative stress.
82 citations
,
March 2013 in “PLoS ONE” Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
74 citations
,
June 2021 in “Frontiers in Cell and Developmental Biology” Human amniotic fluid stem cell-derived exosomes improve wound healing and reduce scarring.
66 citations
,
December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
56 citations
,
March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
54 citations
,
May 2001 in “Journal of Investigative Dermatology” Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
49 citations
,
March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
45 citations
,
October 2019 in “Clinical and Experimental Dermatology” Targeted therapies promoting differentiation could help treat basal cell carcinoma by exhausting cancer stem cells.
45 citations
,
August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.