September 2013 in “Hair transplant forum international” The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.
May 2009 in “Medical and surgical dermatology/Medical & surgical dermatology” Hair and nail conditions can stabilize or improve over time, and new treatments show promise.
July 2022 in “Journal of Cosmetic Dermatology” Isotretinoin with tacrolimus may be more effective short-term for treating frontal fibrosing alopecia than finasteride with tacrolimus.
June 2020 in “Journal of Investigative Dermatology” Leukocyte-rich platelet-rich plasma is safe and can potentially help treat scarring hair loss.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
207 citations
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March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
178 citations
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August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
113 citations
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June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
64 citations
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August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
60 citations
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June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
60 citations
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May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
58 citations
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April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
50 citations
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December 2017 in “British Journal of Dermatology” Different skin cells produce unique materials, which can improve skin substitutes for healing.
48 citations
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January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
48 citations
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December 2022 in “Biomolecules” 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
46 citations
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December 2006 in “Anais Brasileiros de Dermatologia” Acne is the most common skin problem in Brazil, with a need for improved dermatological care and health education, especially for the public sector and black-skinned individuals.
44 citations
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
40 citations
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December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
31 citations
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November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
29 citations
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November 2014 in “Experimental Dermatology” Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.
27 citations
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August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
22 citations
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February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
17 citations
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October 2021 in “Cellular & Molecular Biology Letters” New biomarkers and potential treatments for skin diseases were identified.
9 citations
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August 2024 in “Tissue Engineering and Regenerative Medicine” Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
7 citations
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March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.
4 citations
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January 2026 in “Cell Discovery” Understanding wound healing involves coordinating different phases and areas to improve treatment strategies.
3 citations
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December 2022 in “Cells” Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
2 citations
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November 2025 in “Cells” Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
2 citations
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September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.