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GlossarySkin Hydration

process of maintaining water in skin's outermost layer

Skin hydration refers to the process of maintaining an adequate level of water in the skin's outermost layer, the stratum corneum. Proper skin hydration is crucial for maintaining skin elasticity, smoothness, and barrier function, which helps protect against environmental damage and prevents conditions like dryness, flakiness, and irritation.

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research Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial

5 citations , September 2023 in “Nutrients”

Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.

research Evaluation of lactic acid ferment lysate for the management of oily skin: impact on sebum, hydration, and microbiota

June 2026 in “Frontiers in Physiology”

This study evaluated the effects of a topical cream containing 3% lactic acid ferment lysate VHProbi ® MixP on oily skin over a 60-day period with 42 participants. Results showed significant reductions in sebum production (31.44%), porphyrin levels (44.60%), and pore size (25.03%), alongside improvements in skin hydration (63.68%) and texture (38.43%). Additionally, the cream altered the facial microbiota, increasing α-diversity and shifting bacterial composition, notably reducing Staphylococcus spp. and Cutibacterium spp. while increasing Streptococcus spp. The findings suggest that VHProbi ® MixP may be effective in managing oily skin by reducing hyperseborrhea, enhancing hydration, and modulating the skin's microbial community.

research A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12‐Week Oral Intake of a Supplement Containing Hydrolysed Collagen

10 citations , January 2024 in “Dermatology Research and Practice”

Taking a collagen and vitamin C supplement improves skin and hair health.

research Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects

269 citations , October 2018 in “International journal of biological macromolecules”

Hyaluronic acid is effective for skin rejuvenation and should be a key ingredient in cosmetic products.

research Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice

216 citations , May 2003 in “Journal of Investigative Dermatology”

Glycerol is essential for skin hydration in mice without sebaceous glands.

research Hormone replacement therapy and the skin

138 citations , May 2000 in “Maturitas”

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

research Estrogens and the skin

137 citations , June 2005 in “Climacteric”

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

137 citations , January 2000 in “Skin Pharmacology and Physiology”

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

research Effect of estrogens on skin aging and the potential role of SERMs

120 citations , October 2007 in “Clinical Interventions in Aging”

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

research Protective Effects of Melatonin on the Skin: Future Perspectives

44 citations , October 2019 in “International Journal of Molecular Sciences”

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

research Age-Related Changes in Male Skin: Quantitative Evaluation of One Hundred and Fifty Male Subjects

40 citations , July 2013 in “Skin Pharmacology and Physiology”

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

research Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema

15 citations , September 2018 in “Dermatologic therapy”

Both emollients effectively reduced itching and improved skin moisture in xerotic eczema.

research Evaluation of changes in skin biophysical parameters and appearance after pneumatic injections of non-cross-linked hyaluronic acid in the face

11 citations , March 2018 in “Journal of cosmetic and laser therapy”

Injecting non-cross-linked hyaluronic acid into the face improved skin hydration, texture, pores, and reduced wrinkles.

research Effect of dietary supplementation with INVERSION® femme on slimming, hair loss, and skin and nail parameters in women

11 citations , September 2007 in “Advances in therapy”

INVERSION Femme supplement helped women lose weight, reduce hair loss, and improve skin and nail health.

research Evaluation of a topical treatment for the relief of sensitive skin

9 citations , July 2015 in “Clinical Cosmetic and Investigational Dermatology”

QV Face Rescue Gel effectively soothes sensitive skin and boosts collagen without causing irritation.

Circadian Rhythms on Skin Function of Hairless Rats: Light and Thermal Influences

research Circadian rhythms on skin function of hairless rats: light and thermic influences

8 citations , March 2014 in “Experimental Dermatology”

Light and temperature affect the daily skin function rhythms in hairless rats, with temperature influencing water loss but not skin hydration.

research Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases

6 citations , April 2023 in “Cosmetics”

Exosomes could be effective for improving skin health and treating skin diseases.

research Association between serum melatonin and skin aging in an urban population of Mongolia

6 citations , September 2019 in “Journal of cosmetic dermatology”

Lower melatonin levels are linked to more skin aging.

Evaluation of Biophysical Skin Parameters and Hair Changes in Patients with Acne Vulgaris Treated with Isotretinoin, and the Effect of Biotin Use on These Parameters

research Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters

5 citations , March 2021 in “International Journal of Dermatology”

Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.

Women's Skin Throughout Lifetime: Hormonal Impact and Disorders

research Women's Skin throughout Lifetime

5 citations , January 2014 in “BioMed Research International”

Hormonal status significantly affects women's skin health throughout their lives.

research Managing Menopausal Skin Changes: A Narrative Review of Skin Quality Changes, Their Aesthetic Impact, and the Actual Role of Hormone Replacement Therapy in Improvement

4 citations , August 2025 in “Journal of Cosmetic Dermatology”

Hormone replacement therapy can improve menopausal skin quality, but it's not recommended just for skin due to limited evidence.

The Impact of Different Hair-Removal Behaviors on the Biophysical and Biochemical Characteristics of Female Axillary Skin

research The impact of different hair‐removal behaviours on the biophysical and biochemical characteristics of female axillary skin

4 citations , July 2020 in “International Journal of Cosmetic Science”

All hair removal methods irritate underarm skin and cause dryness, with shaving being less irritating but more drying than plucking or waxing.