research The Bioengineering of Microspheric Skin Organoids and Their Application in Drug Screening
Microspheric skin organoids can be used for drug testing, identifying Minoxidil as a Wnt pathway activator.
Search
for
Sort by
Research
30-60 / 1000+ results
research Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells
Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
research Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration
Stem cell-derived organoids can improve skin healing.
research Merkel cell polyomavirus infection and persistence modelled in skin organoids
Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
research 565 hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction
Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
research Engineering Human Skin with Spatially Defined Hair Peg-Like Structures Using Self-Organizing Composite Organoids and Micropatterned Dermal Scaffolds
research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Modeling aging in a culture dish: towards the development of more sophisticated in vitro models of human skin aging
Advanced lab models are needed to better study human skin aging and develop treatments.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Human hair regeneration using organoids and hair-on-chip technologies
Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
research Bioengineering strategies for regeneration of skin integrity: A literature review
Stem cells and new methods can help heal and regenerate damaged skin.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Skin‐on‐a‐chip strategies for human hair follicle regeneration
New technologies show promise for better hair regeneration and treatments.
research Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro
Mouse skin cells can become sperm-like cells in the lab.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids
Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology
3D human skin models show promise for dermatology but face challenges in standardization and cost.
research Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction
Advances in mechanobiology and immunology could lead to scarless wound healing.
research Generation of Hair Follicle Germs In Vitro Using Human Postnatal Skin Cells
Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
research Advancements in hydrogel-based design and applications of hair follicle organoids
Hydrogel-based hair follicle organoids could help treat hair loss and improve drug testing.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research 1115 Interrogating the gut-skin axis for acne and sebaceous gland health – a case study of nicotinic acid
Taking nicotinic acid supplements might help with acne by affecting the skin's oil glands, but high doses are needed.
research Characterisation, genomic organisation, expression and function of the mEphA1 receptor Tyrosine Kinase
mEphA1 receptor tyrosine kinase is important for skin and hair development and may play a role in certain diseases.
research Evaluating hair growth promoting effects of candidate substance: A review of research methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Functional regeneration strategies of hair follicles: advances and challenges
Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
research 547 CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation
NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
research Blood in the Church: The Inquisition against Hernando Alonso
Mechanical forces are crucial for hair regeneration in skin organoids.