5 citations
,
January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
August 1986 in “Journal of The American Academy of Dermatology” Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.
94 citations
,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
119 citations
,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
25 citations
,
May 2020 in “Aesthetic Surgery Journal” The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
3 citations
,
January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.
52 citations
,
March 2015 in “Tissue Engineering Part C Methods” 3D images of skin show collagen is evenly spread, but elastic fibers are fewer near hair follicles.
11 citations
,
September 2024 in “Journal of the European Academy of Dermatology and Venereology” Hair regrows faster in alopecia areata than skin re-pigments in vitiligo due to differences in stem cells and treatment effects.
92 citations
,
March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
21 citations
,
March 2018 in “American Journal Of Pathology” Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
4 citations
,
December 2020 in “Tissue Barriers” Loricrin affects skin immune function and homeostasis.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.
11 citations
,
November 2023 in “Journal of Functional Biomaterials” The ALGCS/GO30 scaffold effectively boosts mouse spermatogonial stem cell growth.
10 citations
,
February 2014 in “Fitoterapia” Pomiferin may improve skin and hair by increasing important protein production.
4 citations
,
December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
April 2024 in “Cosmetics” Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.
January 2024 in “Advanced Science” New microspheres help heal skin wounds and regrow hair without scarring.
277 citations
,
December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
65 citations
,
November 2013 in “The EMBO Journal” HDAC1 is crucial for skin development and preventing tumors.
35 citations
,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
35 citations
,
September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.
25 citations
,
February 2021 in “Diabetes” Dock5 is important for skin healing and could help treat diabetic wounds.
23 citations
,
November 2018 in “npj Regenerative Medicine” Healing of heart and skin wounds in animals are similar.
22 citations
,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
20 citations
,
November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
2 citations
,
August 2025 in “Pharmaceutics” PN hydrates skin; PDRN heals and regenerates skin and hair.
May 2025 in “Proceedings of the National Academy of Sciences” UTX is crucial for skin differentiation and health, especially in females.
October 2024 in “Acta Biomaterialia” Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.