36 citations
,
October 2015 in “Journal of Cosmetic Dermatology” The study evaluated a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea for its anti-aging effects. In vitro tests showed that the serum increased oxygen consumption, cellular ATP levels, and reduced mitochondrial ROS production in human senescent fibroblasts. In a clinical study involving 32 women with sensitive skin and wrinkles, the serum was applied twice daily for 28 days. Results indicated a significant anti-wrinkle effect in 71% of participants, with visible improvements in 68% after just 7 days. Additionally, there was a notable increase in dermal density and skin elasticity. The serum effectively improved signs of aging by optimizing cell metabolism.
176 citations
,
August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
June 2021 in “Current developments in nutrition” The LustrivaTM BH-002 supplement and hair serum improved women's hair, skin, and nail health and appearance.
17 citations
,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
120 citations
,
October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
60 citations
,
February 1992 in “British Journal of Dermatology” Serum from alopecia patients does not stop hair growth in grafted skin on mice.
6 citations
,
September 2019 in “Journal of cosmetic dermatology” Lower melatonin levels are linked to more skin aging.
2 citations
,
November 2024 in “GSC Biological and Pharmaceutical Sciences” Serums effectively improve skin and hair issues, boosting confidence when used correctly.
December 2025 in “Bioengineering” Sebum is essential for skin health but can cause acne if unbalanced.
July 2022 in “Dermatology Reports” Low zinc levels might be linked to worse outcomes in various skin disorders.
14 citations
,
December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
65 citations
,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively reduces hair loss by decreasing androgen levels.
25 citations
,
November 2015 in “Journal of Dermatological Science” Sebum helps protect human skin from microbes.
December 2023 in “Jurnal Penelitian Pendidikan IPA” PRP heals pockmarked skin better than salmon DNA serum.
1 citations
,
February 2005 in “OakTrust (Texas A&M University Libraries)” Diet B improved dogs' skin and hair condition.
November 2022 in “Journal of Investigative Dermatology” Deleting MPZL3 increases skin oil production and reduces body fat.
11 citations
,
September 1997 in “Archives of Dermatology” Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
2 citations
,
September 1997 in “Archives of Dermatology” January 2008 in “Anhui nongye kexue” Mongolia sheep hair follicles grew well in a serum-free medium for 19 days.
Zinc levels in hair and blood are linked to enzyme activity in people with certain skin conditions.
17 citations
,
August 2010 in “International Journal of Cosmetic Science” Orthosiphon stamineus leaf extract reduces oily skin and improves complexion better than zinc gluconate.
12 citations
,
October 1999 in “Journal of The American Academy of Dermatology” 
93 citations
,
January 2016 in “British Journal of Dermatology” Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.
16 citations
,
January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Low levels of vitamin B12 and ferritin are linked to early hair graying.
March 2025 in “Frontiers in Veterinary Science” Changing light exposure boosts hormone levels and antioxidant activity, improving cashmere growth in goats.
70 citations
,
April 2016 in “Experimental Dermatology” A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.
4 citations
,
November 2023 in “Biological and Pharmaceutical Bulletin” The serum reduced thigh fat and improved skin firmness.
1 citations
,
January 2022 in “PubMed” Autologous serum, a substance from a patient's own blood, is effective in skin treatments for wound healing, skin rejuvenation, acne scars, and hair loss, with low risk of allergies or disease transmission.
1 citations
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September 2016 in “Springer eBooks” Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.
January 2024 in “Genetics in Medicine Open” A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.