518 citations
,
November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
238 citations
,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
113 citations
,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
106 citations
,
August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
61 citations
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October 2013 in “PLoS ONE” Boosting Wnt signaling improves skin wound healing.
56 citations
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November 2022 in “Biomolecules” Targeting macrophages may improve wound healing.
54 citations
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May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
51 citations
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January 2006 in “Wound Repair and Regeneration” MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
47 citations
,
October 2021 in “Journal of Nanobiotechnology” HPDAlR nanoparticles greatly improve skin wound healing without toxicity.
19 citations
,
January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
16 citations
,
December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
14 citations
,
November 2020 in “International Journal of Biological Macromolecules” Mushroom-based scaffolds help heal skin wounds and regrow hair.
12 citations
,
February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
12 citations
,
November 2024 in “Burns & Trauma” Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
12 citations
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September 2007 in “Wound repair and regeneration” Smad2/3-dependent TGF-β signaling increases during wound healing.
11 citations
,
January 2018 in “IET Nanobiotechnology” The scaffolds significantly sped up wound healing in dogs and were safe.
8 citations
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June 2022 in “Frontiers in bioengineering and biotechnology” A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
5 citations
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January 2016 in “Elsevier eBooks” Using a specific binding agent and low doses of FK506 can stimulate stem cells, speeding up skin healing by 25% and improving skin quality in rats and mice.
5 citations
,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
2 citations
,
May 2019 in “Advances in wound care” Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
2 citations
,
January 2022 in “Experimental Dermatology” GDNF signaling helps in hair growth and skin healing after a wound.
1 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
1 citations
,
May 2025 in “International Immunopharmacology” L-borneol helps skin wound healing by promoting stem cell differentiation.
1 citations
,
April 2025 in “Materials Today Communications” The dressing speeds up wound healing by mimicking skin's natural properties.
1 citations
,
February 2024 in “ACS applied bio materials” The new Exo/Gel dressing with stem cell-derived particles helps skin wounds heal faster.
April 2024 in “Vestnik dermatologii i venerologii” Exosomes show promise for diagnosing and treating skin conditions and hair loss.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.
February 1956 in “Bulletin of Experimental Biology and Medicine” Glycogen levels in mouse skin drop after injury but increase during healing, returning to normal within a month.
Plant-derived exosomes show promise for healing skin wounds but need more research and trials.