research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
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research Liposomal systems as drug delivery vehicles for dermal and transdermal applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies
Personalized acne treatments and new therapies show promise for better results.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Hormonal Therapies in Cosmetic Dermatology: Mechanisms, Clinical Applications, and Future Perspectives
Hormonal therapies can improve skin issues by adjusting hormone levels, with future advancements promising better results.
research Hair follicle-inspired therapies for wound healing and scar remodelling
Hair follicles can improve wound healing and reduce scarring.
research Extracellular vesicles derived from embryonic day 13 fetal mouse dermal fibroblasts exhibit potential antifibrotic activity
E13 fetal mouse fibroblast vesicles may help reduce scarring.
research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial
The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
research Surgical Therapies
Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration
The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin
The drug was successfully released into hair follicles using nanocarriers.
research Mesenchymal stromal cell–derived magnetic nanovesicles for enhanced skin retention and hair follicle growth
Magnetic nanovesicles from stem cells can improve hair growth by staying in the skin longer.
research Hidradenitis Suppurativa
The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.
research Epigenetic Mechanisms, Assessment and Therapeutics of Epidermal Stem Cells in Skin Aging
Epigenetic changes in skin cells contribute to aging, but targeting these changes may offer new antiaging treatments.
research Dissolving microneedles: Applications and growing therapeutic potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.
research Dermoscopy Update: Review of its Extradiagnostic and Expanding Indications and Future Prospects
Dermoscopy now helps diagnose various skin, hair, and nail issues, improving patient care and treatment understanding.
research Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream
Ruxolitinib cream effectively targets and treats inflammatory skin diseases.
research Supportive Oncodermatology: Addressing dermatologic adverse events associated with oncologic therapies
Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.
research The green healer: an updated review on the phytochemical profile and therapeutic potential of Aloe vera
Aloe vera is effective for healing, skin, and health due to its beneficial compounds.
research Magistral Galenic Preparations in Modern Dermatology: Our Top 10 Picks for Bridging Therapeutic Gaps
Customized dermatological treatments effectively address gaps in standard products, especially for complex cases.
research 314 Molecular genetic dissection of ILVEN leads to successful targeted therapy
Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Old Wine in New Bottles: Reviving Old Therapies for Alopecia Areata Using Rodent Models
Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.
research Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review
Total glucosides of paeony can help treat skin conditions but need more research for clinical use.
research The role of vitamin D receptor signaling in hair follicle health and alopecia: Current understanding and therapeutic implications
Vitamin D receptor is crucial for hair health and may help treat hair loss.
research Targeted delivery of a poorly water-soluble compound to hair follicles using polymeric nanoparticle suspensions
Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
research Therapeutic Approach to Vaccine-Induced Ischemic Dermatopathy in a Pomeranian Dog with Refractory Alopecia
A tailored treatment improved a Pomeranian dog's skin and hair issues caused by a vaccine.
research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils
The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.