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September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
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December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
January 2023 in “International journal of biological sciences” COX2 and ATP synthase control the size of hedgehog spines.
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April 2021 in “Biomedicines” The engineered skin substitute helped grow skin with hair on mice.
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January 1998 in “Molecular Carcinogenesis” ErbB2 signaling is crucial for skin cell growth and cancer development in mice.
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June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” A boy's skin fragility and sparse hair were caused by a genetic mutation affecting skin cell adhesion.
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December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
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August 2003 in “Journal of comparative neurology” Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
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September 2009 in “Molecular Neurobiology” Removing SIX1 in fat cells reduces skin fibrosis.
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
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February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
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November 2011 in “The Journal of Dermatology” Hair follicle stem cells can help repair nerve injuries.
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March 2022 in “Cell Death and Differentiation” Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
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January 2023 in “Journal of Developmental Biology” Reptile skin protects and prevents water loss, helping them adapt to land.
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April 2023 in “Biochemical Society Transactions” Tissue stiffness helps shape how organisms develop.