research Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear
Stem cell therapy could help regenerate inner ear hair cells to treat hearing loss.
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research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling
3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Biochemistry of epidermal stem cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride
Dutasteride is more efficient than finasteride, but individual results vary.
research Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin
Proper tissue repair in adult skin requires specific histone hypomethylation.
research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance
B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
research Effects of mitotane treatment on human steroid metabolism: implications for patient management
Mitotane changes steroid breakdown, affecting cortisol availability.
research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells
Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research A randomized, double-blind, vehicle-controlled clinical study of hair regeneration using adipose-derived stem cell constituent extract in androgenetic alopecia
ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
research Epidermal keratinocyte stem cells: their maintenance and regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration
Stem cell-derived organoids can improve skin healing.
research Raman spectroscopy and electronic microscopy structural studies of Caucasian and Afro human hair
Hair treatments cause significant structural changes, especially with excessive heat, regardless of ethnicity.
research Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models
Stress worsens Tourette symptoms by increasing allopregnanolone levels.
research Stem cells and aberrant signaling of molecular systems in skin aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration
Tenascin-C and tenascin-W help control stem cell movement and growth in whisker follicles.
research Study of the Efficacy of Korean Red Ginseng in the Treatment of Androgenic Alopecia
Korean red ginseng can significantly increase hair density and thickness in people with androgenic alopecia.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research 13C-NMR study of 4-azasteroids in solution and solid state
4-azasteroids, including finasteride, can inhibit 5α-reductase, helping treat conditions like enlarged prostate and hair loss.
research Studies of Developing Human Hair Shaft Cells In Vitro
research Development of a nude mouse model to study human sebaceous gland physiology and pathophysiology.
The model using human skin on mice helps study human sebaceous glands.
research Electrochemical studies on minoxidil and its determination in tablets by differential-pulse polarography
Method measures minoxidil in tablets accurately and easily.
research Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate
Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
research Stem Cell Therapy for Burns: Story so Far
Stem cell therapy shows promise in improving burn wound healing.