research Other Products Being Developed by Pharmaceutical and Cosmetic Companies
Minoxidil can cause hair growth as a side effect.
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research A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men
New 5% minoxidil foam effectively promotes hair growth and is safe for use.
research Systemic steroids with or without 2% topical minoxidil in the treatment of alopecia areata
Prednisone can regrow hair in alopecia areata, and minoxidil helps maintain it.
research Progesterone-induced spike-wave discharges are inhibited by finasteride
Finasteride blocks progesterone's effect on brain activity linked to epilepsy.
research Finasteride plus doxazosin combination tops in BPH
research Tolerance and safety profile of sublingual minoxidil in the treatment of androgenic alopecia
Sublingual minoxidil is a safe and effective treatment for hair loss, especially in women.
research Weekly azathioprine pulse versus betamethasone oral mini-pulse in the treatment of moderate-to-severe alopecia areata
Weekly azathioprine pulse is a better alternative to corticosteroids for treating alopecia areata due to fewer side effects.
research Antiepileptogenic effects of trilostane in the kainic acid model of temporal lobe epilepsy
Trilostane may help delay epilepsy development by increasing certain brain chemicals.
research Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study
CG2001 is safe, well-tolerated, and a promising treatment for hair loss with fewer side effects.
research Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]
Minoxidil 0.25 mg with spironolactone 25 mg reduces hair loss and improves hair density in women.
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
research Novel causes of drug-induced occupational asthma
Four new substances—minoxidil, ferrimanitol ovalbumin, clarithromycin, and glucosamine-hydrochloride—can cause occupational asthma.
research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double Blind, Placebo-Controlled Trial
research Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque.
Finasteride and minoxidil together promote hair growth better than either alone.
research A randomized, single-blind trial of 5% minoxidil foam once daily versus 2% minoxidil solution twice daily in the treatment of androgenetic alopecia in women
5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Efficacy, safety and dose response of STS01, a topical controlled release nanoparticle formulation (dithranol/Prosilic), in adults with mild to moderate patchy alopecia areata: A randomised, double-blind, multicentre, phase 2 trial
STS01 1% effectively promotes hair regrowth with minimal side effects.
research Effect of finasteride on adrenal steroidogenesis in men.
Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
research Topical minoxidil hair loss therapy may cause chest pains and palpitations,
research Determination of adulteration in hair serums by LC-HRMS §
A new method found unlisted drugs in two popular hair serums, posing a health risk.
research Clinical study of combined prednisone with minoxidil in treatment of the androgenetic alopecia
Using prednisone, zinc, and minoxidil together effectively treats hair loss with long-term benefits and is safe to use.
research Evaluating the safety and effectiveness of minoxidil (5%) with procapil, redensyl, caffeine & transcutol vs plain minoxidil (5%) in androgenetic alopecia
MpowerTM may improve hair growth and satisfaction more than plain minoxidil, with mild side effects.
research Therapeutic potential of isoproterenol in androgenetic alopecia: activation of hair follicle stem cells via the PI3K/AKT/β-Catenin signaling pathway
Isoproterenol may help treat hair loss by activating hair follicle stem cells.
research Pharmacologic properties of minoxidil: a new hypotensive agent.
Minoxidil is a new drug that lowers blood pressure.
research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands
New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.
research Short‐Term, Low‐Dose Spironolactone for Treatment of Hyperandrogenic Symptoms of Polycystic Ovary Syndrome—A Systematic Review
Spironolactone and metformin work similarly for PCOS symptoms, but more research is needed.
research Clinical trial and in vitro study investigating topical application of Zataria multiflora Boiss. and Matricaria chamomilla extracts for androgenetic alopecia
Extracts improve hair growth in alopecia.
research Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.