5 citations
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July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
55 citations
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March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
53 citations
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February 2015 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is essential for normal hair growth and preventing hair loss.
10 citations
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June 2021 in “EMBO reports” When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.
9 citations
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January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
8 citations
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July 2022 in “BMC neuroscience” Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
4 citations
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January 2025 in “The Journal of Cell Biology” Ceramide Synthase 4 is crucial for maintaining hair follicle stem cells and preventing hair loss.
3 citations
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December 2022 in “npj Regenerative Medicine” HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
2 citations
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June 2023 in “PeerJ” Chronic inflammation can cause cancer by making stem cells divide and mutate.
1 citations
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October 2022 in “Molecular therapy” The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
January 2026 in “Figshare” ASLNC168501 may help restore hair growth in androgenetic alopecia by improving hair follicle stem cell function.
January 2026 in “Figshare” ASLNC168501 may help treat hair loss by boosting hair follicle stem cell activity.
September 2025 in “Journal of Investigative Dermatology” SLC3A2 is crucial for hair follicle stem cell function and hair growth.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
January 2025 in “Advances in experimental medicine and biology”
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
June 2026 in “Journal of Investigative Dermatology” Retinoic acids temporarily change skin stem cells to a slower cycle and more differentiated state.
April 2026 in “International Journal of Advanced Biochemistry Research” Aegle marmelos fruit extract can protect against arsenic toxicity in mice.
200 citations
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March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
27 citations
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February 2020 in “EMBO Reports” MEX3A is crucial for maintaining intestinal stem cells in mice.
11 citations
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December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
July 2014 in “European Journal of Cancer” p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.
74 citations
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October 2023 in “Nature Reviews Molecular Cell Biology” November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
July 2025 in “Biotechnology and Bioprocess Engineering” Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
19 citations
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January 2019 in “Molecular Medicine Reports” Store stem cells at 4°C in 10% human serum and use within 2-4 hours for best results.
The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.
The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.
The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.