25 citations
,
March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
21 citations
,
January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
2 citations
,
July 2025 in “Journal of Cosmetic Dermatology” Cosmetic dermatology is improving with new technologies but faces ethical and regulatory challenges.
January 2026 in “Archives of Internal Medicine Research” PRP, exosomes, and physical therapies show promise for hair and tissue repair, but need more research for optimization.
November 2025 in “Cosmetics” Autologous Micrografting Technology effectively improves hair growth and is a safe, promising option for hair restoration.
Balding hair follicles have reduced growth factors and increased inhibitory factors, suggesting new treatment paths for hair loss.
12 citations
,
April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” Fzd2 is important for skin and hair development through various signaling ways.
January 2025 in “PLoS ONE” Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
December 2024 in “Journal of Clinical Medical Research” Regenerative medicine uses combined treatments to boost natural healing and improve health, especially for aging.
April 2024 in “Journal of translational medicine” Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
May 2015 in “Journal of Investigative Dermatology” Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
417 citations
,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
29 citations
,
March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
25 citations
,
November 2014 in “British Journal of Dermatology” Certain transporters are found in human hair follicles and may affect hair growth and loss.
10 citations
,
January 2010 in “Veterinary pathology” A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
9 citations
,
May 2010 in “Journal of Investigative Dermatology” Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.
7 citations
,
January 2024 in “Cancer Research Communications” TAp63 and NRF2 work together to manage oxidative stress, preventing premature aging and aiding skin functions.
5 citations
,
November 2008 in “Advances in Dermatology” The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
375 citations
,
February 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
103 citations
,
January 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
1 citations
,
June 2015 in “Experimental Dermatology” Fat may help skin health and repair, but more research is needed.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
April 2017 in “Journal of Investigative Dermatology” Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
June 1967 in “Journal of Cellular Physiology” The 3D hair follicle model improves understanding of hair growth and drug testing.
May 2026 in “Ibero-American Journal of Health Science Research” Regenerative therapies, including platelet-rich plasma (PRP) and stem cells, are revolutionizing dermatology and aesthetic medicine by offering innovative solutions for tissue rejuvenation and repair. PRP, derived from the patient's blood, is rich in growth factors that stimulate cell proliferation and collagen synthesis, promoting effective tissue regeneration. Stem cells, mainly from bone marrow or adipose tissue, can differentiate into various cell types and actively participate in reparative processes. This narrative review highlights the biological foundations, clinical applications, and recent advances of these therapies, emphasizing their safety, efficacy, and transformative potential in aesthetics. It also discusses current limitations and future prospects, stressing the need for more robust clinical studies to standardize protocols and optimize outcomes, ultimately representing a promising approach to personalized, minimally invasive treatments in regenerative dermatology.
12 citations
,
September 2024 in “JID Innovations” Skin-on-a-chip devices better mimic human skin for research.
38 citations
,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.