200 citations
,
March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
76 citations
,
January 2017 in “World Journal of Stem Cells” Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
33 citations
,
October 2010 in “Journal of Dermatological Science” Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
20 citations
,
November 2021 in “Biomedicines” Adipose-derived stem cells show promise in treatments but need more research for safety, especially in cancer.
2 citations
,
December 2022 in “PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI” Bioceramic and biopolymer composites are promising for advanced wound care, promoting healing and cell growth.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
13 citations
,
September 2014 in “BMC Complementary and Alternative Medicine” Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
15 citations
,
July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
8 citations
,
May 2019 in “Journal of Stem Cells & Regenerative Medicine” Dental pulp stem cells are better for tissue repair, while fat tissue stem cells may be more suited for wound healing and hair growth.
7 citations
,
March 2017 in “Actas Dermo-Sifiliográficas” Several new treatments for different types of hair loss show promise in improving patient quality of life.
18 citations
,
May 2022 in “Stem Cell Research & Therapy” Green OLED light improves stem cell effectiveness for better wound healing.
224 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
31 citations
,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
26 citations
,
July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
3 citations
,
August 2025 in “International Journal of Molecular Sciences” Induced pluripotent stem cells are a major breakthrough in regenerative medicine.
64 citations
,
August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
94 citations
,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
72 citations
,
January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
65 citations
,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
51 citations
,
November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
44 citations
,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
42 citations
,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
39 citations
,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
27 citations
,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
19 citations
,
December 2018 in “Experimental and Molecular Medicine” Small molecule IM boosts hair growth by changing stem cell metabolism.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
18 citations
,
January 2013 in “Journal of Investigative Dermatology” WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.
14 citations
,
February 2020 in “Stem Cells International” Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.