112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
55 citations
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August 2024 in “Heliyon” Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
21 citations
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August 2020 in “Stem Cell Research & Therapy” Stem cell therapy helps heal burn wounds faster in animals.
2 citations
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November 2025 in “Cells” Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
1 citations
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October 2023 in “Journal of plastic, reconstructive & aesthetic surgery” Stem cell-derived conditioned medium is effective in improving hair density and thickness for alopecia treatment.
1 citations
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November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
70 citations
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February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
7 citations
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March 2017 in “Actas Dermo-Sifiliográficas” Several new treatments for different types of hair loss show promise in improving patient quality of life.
3 citations
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July 2025 in “International Journal of Biological Sciences” m6A methylation is crucial for proper wound healing and tissue repair.
3 citations
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June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
January 2026 in “MEDS Clinical Medicine” Biophysical and metabolic factors in skin wounds are crucial for stem cell behavior and skin healing.
October 2025 in “Journal of Translational Medicine” Combining biomaterials and cell pathways can improve hair follicle regeneration.
Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.
April 2015 in “Plastic and Reconstructive Surgery” TLR3 activation helps improve skin and hair follicle healing in mice.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
39 citations
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July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
28 citations
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April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
26 citations
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January 2019 in “Expert Opinion on Investigational Drugs” New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
14 citations
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November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
9 citations
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July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
3 citations
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February 2025 in “Frontiers in Cell and Developmental Biology” Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.
2 citations
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October 2022 in “Journal of Biomedical Science” Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
March 2025 in “World Journal of Stem Cells” Stem cell exosomes may help treat hair loss by promoting hair growth.
February 2025 in “Biochemistry” Stem cell therapy shows promise for treating skin disorders.
August 2023 in “Stem Cell Research & Therapy” Using adipose-derived stem cell media with minoxidil may help regrow hair in men with hair loss.
17 citations
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May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
7 citations
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March 2025 in “Free Radical Biology and Medicine” Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
6 citations
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October 2014 in “International Journal of Molecular Sciences” Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.