research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
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research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Journal Watch
A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
research Severe steroid-dependent idiopathic angioedema with response to rituximab
A woman with severe angioedema improved significantly after treatment with rituximab.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Hepatotoxicity Associated with Anabolic Androgenic Steroids and Selective Androgen Receptor Modulators: A Literature Review
Anabolic steroids and SARMs can cause serious liver damage.
research A New Combination Therapy for Scalp Alopecia Areata: A Study of High Negative Pressure Microdermabrasion + Intralesional Steroids
Combining microdermabrasion with steroid injections improves hair regrowth in scalp alopecia areata.
research A Real-World Study of Steroid-Free Monotherapy with Tofacitinib in Severe and Therapy-Recalcitrant Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Cases: A Retrospective Analysis
Tofacitinib was effective for severe, treatment-resistant hair loss without side effects.
research Topical sodium valproate-loaded nanospanlastics versus conventional topical steroid therapy in alopecia areata: a randomized controlled study
Both treatments for alopecia areata showed similar modest effectiveness.
research Anabolic androgenic steroids impact on cardiovascular risk and cardiovascular events. The literature review
Anabolic-androgenic steroids increase the risk of heart problems.
research Hair and nail involvement in lupus erythematosus
Lupus can cause hair loss and nail changes, with treatments available for both.
research COVID-19 pandemic: what about the gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
research Weekly azathioprine pulse versus betamethasone oral mini-pulse in the treatment of moderate-to-severe alopecia areata
Weekly azathioprine pulse is a better alternative to corticosteroids for treating alopecia areata due to fewer side effects.
research Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.
Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
research Finasteride treatment and neuroactive steroid formation.
Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
research TREATMENT OF ALOPECIA AREATA
Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.
research Telogen effluvium associated with COVID‐19 infection
COVID-19 may cause hair loss due to infection stress or treatments.
research Adolescent hair loss
Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
research A practical approach to feline symmetrical alopecia
The conclusion is to thoroughly test for causes of cat hair loss and treat accordingly, considering medication only after serious conditions are ruled out.
research Retrospective Analysis of Systemic Corticosteroids for Alopecia Areata in Pediatric Patients
Systemic steroids temporarily improve severe alopecia areata in children but often lead to relapse.
research Tumour regression predicts higher risk of sentinel node involvement in thin cutaneous melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Cutaneous Manifestations of Lupus Erythematosus
Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.
research Obstetric Dermatology
The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
research Management of ‘refractory’ skin disease in patients with lupus erythematosus
The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.
research HAIR LOSS AND REGENERATION PERFORMED ON ANIMAL MODELS
Animal models are crucial for learning about hair loss and finding treatments.
research A 17-Year-Old Mother Seeking Contraception
The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.
research Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol
Early NAS level changes affect alcohol consumption vulnerability.
research Alopecia Areata. Current situation and perspectives
Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.
research LAWSONIA INERMIS L.: AN UPDATED REVIEW OF THE ETHNOBOTANICAL, PHYTOCHEMICAL, PHARMACOLOGICAL, AND TOXICOLOGICAL ASPECTS IN UNANI MEDICINE
Henna has many medicinal uses but needs more research to confirm its benefits.
research Contemporary techniques of hair replacement
In 1981, the punch graft technique was the main method for hair transplantation, and medical treatments for baldness were not very effective.