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A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.

New compounds may help treat prostate issues without affecting androgen receptors.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

PCOS is likely inherited in families, increasing risk for first-degree relatives.

Gut microbiota and metabolic pathways may play a key role in PCOS development.

A new method accurately measures long-term hormone levels in hair.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Overexpression of COX-2 in mice skin causes abnormal skin and hair development.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

Body hair isn't a good substitute for scalp hair in steroid analysis.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Two specific genes are more active during hair growth in mice.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Certain genes are linked to wool follicle structure and function, but not hair cycle regulation.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Researchers found genes for cysteine-rich proteins that form the protective layer of hair in humans and sheep.

Steroid hormones can be preserved in ancient hair, revealing insights into past health and fertility.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The animal models successfully simulated dry eye related to sex steroid deficiency.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.

Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Pesticides can cause reproductive and adrenal health issues.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.