research Drug Repurposing Patent Applications April–June 2021
Drug repurposing shows promise for treating many medical conditions.
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240-270 / 1000+ resultsresearch Intravenous Transplantation of Human Hair Follicle-Derived Mesenchymal Stem Cells Ameliorates Trabecular Bone Loss in Osteoporotic Mice
Human hair follicle stem cells can help treat bone loss in osteoporosis.
research Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells
Stress can cause hair to turn gray by depleting stem cells.
research European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
research An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin
The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.
research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?
TGase 3 helps build hair structure by forming strong bonds between proteins.
research Lipid Droplets from Plants and Microalgae: Characteristics, Extractions, and Applications
Plant and algal lipid droplets are promising for natural oil production but need better extraction methods.
research Exosomes in stroke management: A promising paradigm shift in stroke therapy
Exosome therapy could revolutionize stroke treatment, but more research is needed for human use.
research Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration
PRP helps skin heal, possibly through special cells called telocytes.
research Evolution and Trends of Facial Plastic Surgery and Facial Aesthetic Procedures in India: From Awakening to Revival
Facial plastic surgeries and aesthetic procedures are becoming more popular in India, with a preference for non-surgical options and effective treatments for facial enhancement and hair loss.
research Poly-D,L-Lactic Acid Filler Increases Hair Growth by Modulating Hair Follicular Stem Cells in Aged Skin
Poly-D,L-lactic acid boosts hair growth in aged skin by activating hair follicle stem cells.
research Rat Hair Follicle Stem Cell-Derived Exosomes: Isolation, Characterization and Comparative Analysis of Their In Vitro Wound Healing Potential
Exosomes from rat hair follicle stem cells may help heal wounds and regenerate skin.
research eLife Assessment: The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling
Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
research Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction
Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.
research The future in the litter bin – bioconversion of food waste as driver of a circular bioeconomy
Turning food waste into useful products is key for a sustainable economy.
research Human Fibroblast‐Derived Matrix Hydrogel Accelerates Regenerative Wound Remodeling Through the Interactions with Macrophages
A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
research Smart Bio-Polymeric Matrix for Accelerated Wound Healing and Tissue Regeneration
The material combining eggshell protein and scaffold helps wounds heal faster and regenerates tissue effectively.
research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications
Nanocarriers can improve drug delivery through the skin by overcoming barriers.
research Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin, and Hair Growth Modulation by Neuropeptides
Neuropeptides affect hair growth, with some speeding it up and others slowing it down.
research Dynamic Plasticity of Axons within a Cutaneous Milieu
Hair clipping can trigger axon growth and changes in the skin.
research Strontium ranelate promotes chondrogenesis through inhibition of the Wnt/β-catenin pathway
Strontium ranelate helps cartilage growth by blocking a specific cell pathway.
research Effect of composite biodegradable biomaterials on wound healing in diabetes
Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.
research Two-ligand priming mechanism for potentiated phosphoinositide synthesis is an evolutionarily conserved feature of Sec14-like phosphatidylinositol and phosphatidylcholine exchange proteins
A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.
research Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers
Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
research Advances in Microengineered Platforms for Skin Research
Skin-on-a-chip devices better mimic human skin for research.
research Cell death in skin function, inflammation, and disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research Photobiomodulation therapy
Photobiomodulation therapy can reduce pain and inflammation and help heal tissues, but more research is needed to improve its effectiveness and safety.