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Chemistry42 effectively creates and optimizes new molecules for drug discovery.
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720-750 / 1000+ resultsresearch Microneedles as transdermal drug delivery system for enhancing skin disease treatment
Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
research Immunosuppressive treatment for proliferative lupus nephritis
Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.
research Vitiligo - Part 2 - classification, histopathology and treatment
New vitiligo treatments focus on controlling immune damage and restoring skin color.
research Development and Assessment of an Artificial Intelligence–Based Tool for Skin Condition Diagnosis by Primary Care Physicians and Nurse Practitioners in Teledermatology Practices
The AI tool helped primary care doctors and nurse practitioners diagnose skin conditions more accurately.
research The most recent advances in understanding and managing hidradenitis suppurativa
Better understanding and new treatments for hidradenitis suppurativa are emerging, but more research is needed.
research Serum-Based Assessment of Alopecia Areata Response to Treatment Using ATR-FTIR Spectroscopy
ATR-FTIR spectroscopy could help monitor alopecia areata treatment response non-invasively.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, 25–28 February 2023, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.
research Experts’ view on the management of scalp seborrheic dermatitis in Italy
Use topical antifungals and selenium disulfide for scalp seborrheic dermatitis, with corticosteroids for severe cases.
research Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force “Dermatology for Cancer Patients” International Study
Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
research Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database
People with Alopecia Areata have more herpes simplex infections but similar rates of cancer, blood clots, and heart disease compared to those without it.
research Trailing the Path to Preventive Oncology
Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.
research Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US
Vitiligo patients have higher risks of autoimmune diseases, infections, and skin cancer.
research Mendelian randomization studies of testosterone exposure: A systematic review
Testosterone's health effects are complex and not definitively understood.
research Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study
Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.
research Beyond vitiligo guidelines: combined stratified/personalized approaches for the vitiligo patient
Personalized treatment plans improve vitiligo care.
research Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening
The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
research Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds
Transglutaminase activity is important for skin and is found in both mammals and birds.
research 76976 Association of Depression with Finasteride Stratified by Dosage and Diagnosis: A Retrospective Cohort Study Using the TriNetX Database
Finasteride may lower depression risk in younger men with hair loss but increase it in older men with prostate issues.
research Baseline Neutrophil-to-Lymphocyte Ratio Stratifies Early Trichoscopic Response to Platelet-Rich Plasma–Based Regimens in Non-Scarring Alopecia: A Real-World Cohort with Internal Validation Using an Interpretable Neural Network
A high neutrophil-to-lymphocyte ratio may predict poor response to hair loss treatment.
research Commentary on Clinical Application of Cultured Stratified Epithelial Sheets Grown Under Feeder or Feeder-Free Conditions for Stable Vitiligo
research Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFα expression in transgenic mice
research Characterization of post-COVID syndrome by self-perceived symptom severity stratified by infection wave: beyond COVID, a prospective, multicenter cohort study in Germany
Most people with post-COVID syndrome experience symptoms like fatigue, but Omicron variants cause fewer persistent symptoms.
research Cardiometabolic comorbidities associated with androgenetic alopecia: Findings from a sex-stratified, propensity-matched national cohort
Androgenetic alopecia is linked to higher cholesterol in both sexes and obesity in women.
research Incident Rosacea and Related Dermatoses in Estrogen-Exposed Females: A Large-Scale Age-Stratified Cohort Study
research Treatment Patterns and Health-Related Quality of Life in Patients with Alopecia Areata Stratified by Disease Severity in the USA
More severe alopecia areata can lower quality of life.
research 42380 FFA and Personal Care Product Use, An Investigation into Hair Styling and Stratified Gender Analysis of Facial Sunscreen and Moisturizer: A Systematic Review and Meta-Analysis
Sunscreen use is linked to frontal fibrosing alopecia, especially in males.
research Dermatological changes in a prospective cohort of acutely ill, hospitalised Malawian children, stratified according to nutritional status
Skin changes were less common, and photo assessments were unreliable.
research IS AGE MORE THAN JUST A NUMBER? CHARACTERISTICS OF MEN PRESENTING FOR REPRODUCTIVE UROLOGY FERTILITY EVALUATION IN NORTH AMERICA STRATIFIED BY AGE GROUPS
Older men have different fertility histories and factors affecting fertility, suggesting they may benefit from earlier fertility evaluations.
research Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells
Hair follicle stem cells can become corneal-like cells, potentially helping restore vision.