221 citations
,
July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” BMAL1 controls skin cell growth and UV damage risk, peaking at night.
207 citations
,
July 2006 in “Development” MTS24 marks a new type of skin cell that helps hair growth and repair.
165 citations
,
January 2006 in “Molecular Medicine” Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.
154 citations
,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
129 citations
,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
124 citations
,
July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
122 citations
,
December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
98 citations
,
December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
86 citations
,
August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
67 citations
,
June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
67 citations
,
December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
63 citations
,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
60 citations
,
November 2023 in “Biology” Aging skin causes inflammation that affects the whole body.
52 citations
,
January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
50 citations
,
April 2021 in “Frontiers in Immunology” New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
39 citations
,
February 2024 in “Small” Microneedles are becoming essential tools in medicine for sensing, drug delivery, and communication.
37 citations
,
December 2022 in “Acta Pharmaceutica Sinica B” Smart delivery methods for CRISPR gene editing are crucial for clinical success.
32 citations
,
August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
32 citations
,
June 2024 in “Pharmaceutics” Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.
30 citations
,
November 2024 in “ACS Materials Au” Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.
29 citations
,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
25 citations
,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
18 citations
,
October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
17 citations
,
May 2023 in “Pharmaceutics” Microneedles can precisely deliver cancer treatments with fewer side effects.
16 citations
,
October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
16 citations
,
January 2010 in “Springer eBooks” 15 citations
,
December 2020 in “The Journal of General Physiology” Acid can block TRPV3 from outside the cell but boost its function from inside.
12 citations
,
November 2024 in “Burns & Trauma” Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
12 citations
,
August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.