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March 2019 in “Experimental Dermatology” A wide range of proteins are integrated into the skin's protective layer.
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January 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.
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August 2014 in “Colloids and surfaces. B, Biointerfaces” Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.
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January 2006 in “Journal of Investigative Dermatology” Transferrin receptor expression increases iron in mouse skin cells without causing damage.
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January 2001 in “Bioscience Biotechnology and Biochemistry” Ubiquitin, a protein, is found in hair, nails, and skin.
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January 2023 in “Langmuir” Solubility in skin changes with hydration, affecting chemical absorption.
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May 2024 in “Tissue Barriers” The skin's outer layer relies on lipids and proteins to protect against damage.
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July 2017 in “Microscopy and Microanalysis” Iron oxide nanoparticles mainly enter the skin through hair follicles and sebocytes, not the dermis.
July 2026 in “International Journal of Drug Delivery Technology” SCLL improves finasteride delivery for better hair growth in treating hair loss.
April 2023 in “Journal of Investigative Dermatology” New method measures skin cell turnover quickly and effectively, showing turnover slows with age and responds more to treatments in older skin.
January 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” Argan oil-based nano carriers could potentially deliver caffeine to hair follicles to treat hair loss.
January 2013 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” Hydrophobized silica nanoparticles penetrate the skin's outer layer more effectively, while hair follicle density doesn't impact their accumulation.
Equine hoof progenitor cells can help develop therapies for hoof diseases like laminitis.
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
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December 2005 in “Journal of controlled release” P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
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January 1995 in “Birkhäuser Basel eBooks” Human hair growth and structure are influenced by keratin proteins, genes, melanin, and lipids.
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July 2014 in “Molecular pharmaceutics” New micelle nanocarriers deliver Tacrolimus more effectively to skin layers for psoriasis treatment than the current Protopic ointment.
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August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
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April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
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April 2017 in “International Journal of Nanomedicine” Ethosomes are effective for delivering drugs through the skin by penetrating deeply and targeting hair follicles.
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September 2004 in “Clinics in dermatology” Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.
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May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
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January 2007 in “Skin Pharmacology and Physiology” Caffeine in shampoo quickly enters the body through hair follicles.
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August 2024 in “Acta Pharmaceutica Sinica B” Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
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November 2014 in “Journal of Biomedical Optics” Silver nanoparticles can penetrate porcine skin up to about 15.6 μm, possibly through hair follicles.