Search

for
Search:

Did you mean Subcutaneous Tissue?

GlossarySubcutaneous Tissue

layer of fat and connective tissue beneath the skin

Subcutaneous tissue, also known as the hypodermis, is the layer of tissue directly beneath the skin (dermis). It consists primarily of fat and connective tissue, providing insulation, energy storage, and cushioning to protect underlying muscles and bones. This layer also contains larger blood vessels and nerves, playing a crucial role in thermoregulation and sensation.

Related Terms

Sort by

Research

30 / 1000+ results

Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome

research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)

58 citations , January 2013 in “The Journal of Clinical Endocrinology and Metabolism”

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

research Melanocyte progenitor cells reside in human subcutaneous adipose tissue

18 citations , August 2021 in “PLoS ONE”

Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.

Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Visceral and Subcutaneous Adipose Tissues of Patients with Polycystic Ovary Syndrome Is Associated with Adiposity

research Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity

18 citations , December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology”

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

research Increase in subcutaneous adipose tissue in the frontal scalp may be associated with androgenetic alopecia and metabolic syndrome.

June 2023 in “PubMed”

Thicker scalp fat may link hair loss with metabolic syndrome.

research Tracing the Change and Contribution of Subcutaneous Adipose to Skin Expansion Using a Luciferase-Transgenic Fat Transplantation Model

4 citations , May 2023 in “Plastic & Reconstructive Surgery”

Adipose tissue helps skin expand by increasing blood vessels and cell growth.

research Dermal white adipose tissue: Development and impact on hair follicles, skin defense, and fibrosis

3 citations , September 2024 in “The FASEB Journal”

Dermal white adipose tissue helps regulate hair growth, protect skin, and aid wound healing.

Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin

research Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin

128 citations , October 2011 in “Development”

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

research Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice

32 citations , January 2010 in “Journal of Dermatological Science”

Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.

research Age-related changes in the dorsal skin histology in Mini and Wistar rats.

20 citations , April 2002 in “PubMed”

Mini rats have thinner skin, more fat, and different hair cycles than Wistar rats due to lower growth hormone levels.

research Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

6 citations , October 2020 in “Frontiers in cell and developmental biology”

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

research Lipedematous Alopecia: Clinical, Histopathological, and Trichoscopic Findings of a Single Case and Review of the Literature

2 citations , January 2019 in “Case Reports in Dermatology”

A 66-year-old woman's thick scalp and hair loss were confirmed as lipedematous alopecia, a rare condition possibly influenced by genetics, with no effective treatment known.

research Clinicopathologic and Morphologic Analysis of the Adrenal Gland in Pomeranians with Non-Illness Alopecia

2 citations , January 2005 in “The Japanese Journal of Veterinary Dermatology”

Abnormal adrenal function is not the cause of alopecia in Pomeranians; it may be due to breed-specific hormones.

research Cell-free fat extract improves embryo development and clinical outcomes in older women with previous in-vitro fertilization failure

1 citations , January 2025 in “Reproductive Biology and Endocrinology”

Cell-free fat extract may boost IVF success in older women with past failures.

research Congenital Lipedematous Alopecia in a 6-Year-Old Asian Boy

1 citations , November 2023 in “Indian Journal of Dermatology”

A 6-year-old Asian boy has a rare scalp condition causing hair loss and thickening, with unclear causes and no effective treatment.

Essential Fatty Acid Deficiency in a Patient with Vascular Ehlers-Danlos Syndrome

research Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19)

1 citations , June 2019 in “Current developments in nutrition”

A patient with Ehlers-Danlos Syndrome improved after treatment for fat malabsorption and essential fatty acid deficiency.

research Serum irisin level in patients with acne vulgaris

January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences”

Patients with acne vulgaris have lower serum irisin levels.

research Normal histology of the skin

January 2020 in “프로그램북(구 초록집)”

The skin has two main layers, the epidermis and dermis, which work together and are essential for diagnosing skin conditions.

Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages

research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages

September 2017 in “Journal of Investigative Dermatology”

Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.

research Acquired progressive kinking of the hair in the setting of Parry-Romberg Syndrome

May 2015 in “Journal of The American Academy of Dermatology”

A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.

research Skin aging as a mechanical phenomenon: The main weak links

41 citations , May 2018 in “Nutrition and healthy aging”

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

research Getting under the skin of hair aging: the impact of the hair follicle environment

20 citations , May 2020 in “Experimental Dermatology”

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

research General theory of skin reinforcement

18 citations , August 2017 in “PLOS ONE”

Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.

research Two-Stage Procedure to Correct Scalp and Facial Scars—Autologous Fat Grafting Before Hair Grafting

2 citations , September 2019 in “Dermatologic Surgery”

The two-step procedure of fat grafting followed by hair grafting improves scalp and facial scar correction.

research Does fat get you skinny?

1 citations , June 2015 in “Experimental Dermatology”

Fat may help skin health and repair, but more research is needed.

research Defining dermal adipose tissue

218 citations , May 2014 in “Experimental Dermatology”

Skin fat cells help with skin balance, hair growth, and healing wounds.

research Generation of functionally active resident macrophages from adipose tissue by 3D cultures

2 citations , June 2024 in “Frontiers in Immunology”

3D cultures can create active macrophages from fat tissue.

research Aging of hair follicle stem cells and their niches

2 citations , November 2022 in “Journal of Biochemistry and Molecular Biology”

Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

research Hair follicle growth by stromal vascular fraction-enhanced adipose transplantation in baldness

July 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)”

SVF-enhanced fat injections may effectively treat baldness by promoting hair growth.

research Global Adiposity Rather Than Abnormal Regional Fat Distribution Characterizes Women with Polycystic Ovary Syndrome

149 citations , December 2007 in “The Journal of Clinical Endocrinology and Metabolism”

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

research The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system

8 citations , February 2023 in “American Journal of Physiology-Cell Physiology”

Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.