January 2026 in “Journal of Cosmetic Dermatology” Menopause reduces skin fat, but treatments like magnolol and PLLA-SCA can help restore skin health.
2 citations
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June 2017 in “Journal of The American Academy of Dermatology” The type of PCOS a woman has doesn't strongly predict her skin or metabolic symptoms; obesity is a more important factor.
4 citations
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March 2020 in “BMC Research Notes” Skin tags in obese individuals may indicate higher cardiovascular risk.
136 citations
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September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
April 2017 in “Journal of Investigative Dermatology” Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
November 2016 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” The VMH AMPK-SNS-BAT axis may help treat cachexia and obesity.
December 2019 in “Thèses en ligne de l'Université Toulouse III (Université Toulouse III)” EGM2 and SOX2 help form beige adipocytes by maintaining ASC immaturity and activating brown adipocytes.
September 2023 in “The Journal of Dermatology” Bariatric surgery improved many skin conditions in obese patients but caused hair loss in some and decreased facial oil and skin elasticity.
December 2025 in “Reports of Morphology” Men with alopecia areata have different body fat distribution compared to healthy men.
32 citations
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January 2017 in “PLoS ONE” Adiponectin boosts lipid production in skin cells, potentially helping treat skin conditions with low sebum.
November 2019 in “Клітинна та органна трансплантологія” Adipose-derived stem cells are useful in aesthetic medicine and dermatology for improving skin and tissue appearance.
June 2023 in “International Journal of Research in Dermatology” Weight loss from bariatric surgery improved certain skin conditions.
1 citations
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December 2021 in “Cureus” Overweight PCOS patients often have skin issues like acne, but all PCOS patients should get lifestyle advice.
January 2019 in “Dermatologic Surgery”
3 citations
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January 2020 in “Indian Dermatology Online Journal” Skin problems in patients with polycystic ovarian disease are linked to body weight, blood sugar, and hormone levels.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
March 2026 in “Current Research in Diabetes & Obesity Journal” Skin conditions can signal diabetes and insulin resistance.
January 2013 in “프로그램북(구 초록집)” Adipose stem cell-conditioned media improved hair density and thickness in women with hair loss.
1 citations
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September 2018 in “Vestnik Vitebskogo gosudarstvennogo medicinskogo universiteta”
18 citations
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June 2018 in “Journal of The American Academy of Dermatology” Fat tissue treatments may help with wound healing and hair growth, but more research with larger groups is needed to be sure.
6 citations
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January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
November 2024 in “Cureus” Many female medical students in Saudi Arabia show signs of insulin resistance linked to increased waist size.
April 2016 in “JAMA Dermatology” Acne is not a key diagnostic feature for PCOS, postadolescent men with acne may have insulin resistance, melanoma patients often have few moles, tumor size in CSCC indicates higher risk of serious outcomes, and hidradenitis suppurativa is linked to higher risk of heart problems and death.
April 2016 in “Journal of The American Academy of Dermatology” Women with PCOS often have hirsutism and skin changes, which indicate a need for metabolic health checks.
February 2020 in “Research Square (Research Square)” Skin tags in obese individuals may indicate a higher risk of heart disease and diabetes.
April 2016 in “Journal of The American Academy of Dermatology” Hirsutism and acanthosis nigricans are reliable skin signs of PCOS linked to metabolic issues, while acne is not a reliable marker of the condition.
March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” Insulin resistance significantly contributes to the development and severity of certain chronic skin diseases.
7 citations
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February 2018 in “Journal of Investigative Dermatology” Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
July 2025 in “Journal of Investigative Dermatology” Acne involves increased lipid production and inflammation, affecting skin cell behavior and treatment resistance.