September 1961 in “Archives of Dermatology” Lichen sclerosus et atrophicus is generally not considered precancerous, but there are exceptions.
6 citations
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January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
1 citations
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January 2009 A 25-year-old Malay fireman had skin bumps on his neck that were removed successfully after other treatments failed.
June 2025 in “British Journal of Dermatology” Nail abnormalities in children can indicate deeper health issues.
January 2025 in “Indian Dermatology Online Journal” A 27-year-old female with systemic lupus erythematosus (SLE) presented with chilblain lupus erythematosus (CHLE) and multi-melanonychia striata, a rare condition involving dark, vertical nail striations. Her symptoms included itchy, dark lesions on the face and extremities, painful toe lesions, diffuse hair loss, and polyarthralgia. The patient met the diagnostic criteria for SLE and CHLE, with dermoscopic and histopathological findings supporting the diagnosis. Treatment included oral prednisolone, hydroxychloroquine, topical clobetasol, and antihistamines, leading to improvement. The case highlights the rarity of multi-melanonychia striata in SLE and the importance of recognizing CHLE, which can mimic ordinary chilblains.
33 citations
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March 1994 in “PubMed” High ODC and low K1 and K10 may indicate early skin tumors in mice.
January 2007 in “Linchuang pifuke zazhi” A 15-year-old boy had a rare skin growth on his buttock.
2 citations
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July 2022 in “Cureus” A rare skin disorder affecting the face was found in a 28-year-old Saudi man.
January 2025 in “Clinical Case Reports” Follicular porokeratosis may be linked to diabetes and can lead to hair loss.
January 2024 in “Dermatology Practical & Conceptual” Spotted lunula may help identify alopecia areata.
September 2024 in “Journal of Medical Case Reports” People with keratosis pilaris might be more likely to get a rare type of tinea versicolor.
5 citations
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January 2018 in “Indian Dermatology Online Journal” A brown shadow seen in dermoscopy is a marker for lichen nitidus.
17 citations
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January 2011 in “Indian journal of dermatology, venereology, and leprology” A rare genetic skin condition usually affecting males was found in a 9-year-old girl.
April 2013 in “Journal of the American Academy of Dermatology” Diabetic patients often have ingrown nails due to obesity, high blood pressure, past injuries, bad nail trimming, nail fungus, weak foot pulse, and weak knee reflex.
December 2025 in “Cureus” Topical treatments like AHAs, BHAs, and urea may help keratosis pilaris, but evidence is limited.
35 citations
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September 2006 in “American Journal Of Pathology” Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.
4 citations
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January 2025 in “Clinical Cosmetic and Investigational Dermatology” Papular acantholytic dyskeratosis of the vulva is a rare, benign skin condition that can be managed conservatively.
1 citations
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March 2006 in “Journal of Cosmetic Dermatology” The woman's forehead lesion was caused by ointment use and resolved with treatment.
Patients with graft-versus-host disease often have nail changes related to the nail matrix, with severity not linked to skin condition.
1 citations
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January 2015 in “Journal of clinical case reports” KFSD causes scarring hair loss and skin roughness, mainly in males.
February 2020 in “Definitions” Mutations in the KRT16 gene can cause skin and nail disorders.
October 2023 in “Indian dermatology online journal” The young woman has a benign, hereditary skin condition with no signs of a more serious syndrome.
3 citations
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September 2020 in “Case reports in dermatological medicine” Misdiagnosing kerion as a bacterial infection can lead to unnecessary surgery and permanent hair loss.
2 citations
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June 2013 in “Journal of Dermatological Case Reports” Olmsted syndrome is a rare skin disorder causing thickened skin and other symptoms.
3 citations
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April 2017 in “Journal of Investigative Dermatology” Dermoscopy is useful for diagnosing facial actinic keratosis by identifying specific skin patterns.
January 2003 in “Linchuang pifuke zazhi” A benign skin tumor was removed from a man's leg, and it didn't come back after 9 months.
July 1979 in “Archives of Dermatology” A 68-year-old woman with benign mucous membrane pemphigoid has eye, mouth, and skin issues, including thick plaques and nail changes.
1 citations
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January 2013 in “Springer eBooks” The document concludes that skin and nail changes can indicate various underlying health conditions.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” Actinic prurigo cheilitis can occur in elderly Asians and can be treated with hydrocortisone cream and sun protection.
1 citations
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January 2019 in “Dermatology Online Journal” A rare skin condition appeared on a 19-year-old woman's scalp.