research Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects
Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
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research Non-competitive androgen receptor inhibition in vitro and in vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
research Thyroid receptor agonists for the treatment of androgenetic alopecia
Thyroid receptor agonists may treat male pattern baldness without harmful side effects.
research The pharmacology of methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABAAReceptor Function and Seizure Susceptibility
Stress increases neurosteroids that help prevent seizures.
research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures
EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
research Hidradenitis Suppurativa in Children and Adolescents: A Review of Treatment Options
More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.
research Madarosis: A marker of many Maladies
Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
research Inflammatory loops in the epithelial–immune microenvironment of the skin and skin appendages in chronic inflammatory diseases
Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
research Management of hidradenitis suppurativa:
Treating hidradenitis suppurativa needs long-term care and teamwork among doctors, but there's a lack of strong guidance on how to do it.
research Ichthyosis
The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
research Evidence-based approach to cutaneous hyperandrogenism in women
The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
research Nanoparticles in Cancer Treatment: A Narrative Review
Nanoparticles improve cancer treatment by reducing side effects and targeting cancer cells better.
research TOXIC EPIDERMAL NECROLYSIS
Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
research Protopanaxatirol type ginsenoside Re promotes cyclic growth of hair follicles via inhibiting transforming growth factor β signaling cascades
Ginsenoside Re from ginseng may help hair grow by blocking a specific growth-inhibiting pathway.
research Vitamin D and the skin: Physiology and pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis
Future acne treatments should aggressively target inflammation to prevent scarring.
research Repurposing of approved cardiovascular drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Ablative Fractional Resurfacing in Topical Drug Delivery: An Update and Outlook
Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
research Structural insights into SARS-CoV-2 spike protein and its natural mutants found in Mexican population
Mutations in the spike protein affect drug binding and effectiveness.
research Female Androgenetic Alopecia: An Update on Diagnosis and Management
FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.
research The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation
The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
research Emerging Therapies for Acne Vulgaris
New acne treatments show promise as alternatives to traditional therapies.
research Retinoids for Chemoprophylaxis of Nonmelanoma Skin Cancer
Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.
research The spectrum of nephrocutaneous diseases and associations
Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.
research Epidemiology and Management of Acne in Adult Women
Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.