research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
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420-450 / 1000+ results research Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile
There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
research Alopecia Areata. Current situation and perspectives
Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.
research GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing
GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
research Regulatory T Cells in Autoimmune Diseases and their Potential
Enhancing regulatory T cells may help treat autoimmune diseases like alopecia areata.
research Advances in genetic and molecular understanding of Omenn syndrome - implications for the future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research Dermatologie care behind bars
The first in-prison dermatology clinic in the U.S. faced challenges and found certain skin conditions common among inmates, with rare cases of serious skin cancer.
research Nanoscale microenvironment engineering for expanding human hair follicle stem cell and revealing their plasticity
A new method was developed to grow and maintain human hair follicle stem cells for hair reconstruction.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
research 042 Characterization of Pathogenic CD8+ T Cells in an adoptive transfer Mouse Model of Alopecia Areata in C3H/HeJ mice
Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
research Lichen planus – A refractory autoimmune disorder
Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.
research A Low Dose of Rapamycin Promotes Hair Cell Differentiation by Enriching SOX2+ Progenitors in the Neonatal Mouse Inner Ear Organoids.
A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.
research 185 Regulatory γδ T cells protect human scalp hair follicles from alopecia areata in vivo
γδTregs can protect hair follicles from alopecia areata and may help regrow hair.
research scMC learns biological variation through the alignment of multiple single-cell genomics datasets
scMC effectively separates biological signals from technical noise in single-cell genomics data.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Fibroblast growth factors: key players in regeneration and tissue repair
Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Endogenous retinoids in the hair follicle and sebaceous gland
Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
research Unveiling the Potential of Single‐Cell Encapsulation in Biomedical Applications: Current Advances and Future Perspectives
Single-cell encapsulation shows promise for medical use but faces production challenges.
research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Lgr5 marks cycling, yet long-lived, hair follicle stem cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research More than one way to skin . . .
Skin stem cells help repair damage and maintain healthy skin.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Biochemistry of epidermal stem cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Cholesterol homeostasis: Links to hair follicle biology and hair disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.