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November 2018 in “Journal of Allergy and Clinical Immunology” People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
277 citations
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December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
188 citations
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December 2020 in “Foods” Polyphenols in plant foods help prevent diseases and have potential uses in food, cosmetics, and more.
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November 2008 in “Expert Review of Endocrinology & Metabolism” Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
107 citations
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March 2014 in “BoneKEy Reports” Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
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May 2020 in “Journal of Functional Morphology and Kinesiology” Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.
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January 2020 in “Journal of Nanobiotechnology” Nanomaterials can aid tissue repair and healing but need more safety research.
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March 2018 in “Molecules/Molecules online/Molecules annual” L-Cysteine may have health benefits, but its effectiveness is still debated due to limited clinical trial data.
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July 2022 in “Frontiers in Systems Biology” Modern lifestyles harm beneficial microbes, affecting health.
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April 2018 in “Oncotarget” Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
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January 2020 in “International Journal of Molecular Sciences” PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
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March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
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January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
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October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
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December 2022 in “Pharmacological Reviews” Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
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April 2023 in “Aging Cell” Targeting cellular senescence may improve skin aging and disorders.
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August 2013 in “International Journal of Women's Health” Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
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May 2020 in “Frontiers in immunology” Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
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October 2019 in “Biomolecules” Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.
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December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
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August 2022 in “Pharmaceutics” Combining letrozole and quercetin in spanlastics may improve breast cancer treatment.
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January 2020 in “Frontiers in Genetics” PDGFC gene may help select goats with desirable curly wool traits.
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June 2016 in “Journal of Tissue Engineering and Regenerative Medicine” Microcolumn grafting can effectively regenerate full-thickness, functional skin without scarring.
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November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
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January 2021 in “Frontiers in Cell and Developmental Biology” Hypoxia and epigenetics are crucial for cell growth and tissue regeneration.
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July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
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March 2022 in “Biomedicines” Enhancing antioxidant responses can improve treatments for various diseases.