research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
Activated LEF/TCF complexes are crucial for hair development and cycling.
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research Heterogeneity of neural crest-derived melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches
Exogenous stem cells can effectively integrate into hair follicles, promoting hair growth.
research 613 Assessment of the induction and morphogenic potential of human hair matrix cells and dermal papilla fibroblasts ex vivo
Human hair matrix cells and dermal papilla fibroblasts can form early hair follicle structures but don't produce hair shafts yet.
research 5. 周産期チーム医療におけるソーシャルワークの役割 : 子どもと家族のしあわせへの貢献をチームで目指す中で(メインシンポジウム これからの周産期チーム医療の展開,第50回日本母性衛生学会総会)
DPC-Exos can help regenerate hair follicles and heal wounds by activating the Wnt/β-catenin pathway.
research Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate
TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
research Pten loss in Lgr5+ hair follicle stem cells promotes SCC development
Loss of Pten in certain hair follicle stem cells increases skin cancer risk.
research Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells
PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.
research Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
research P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression
P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.
research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling
EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
research OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases
OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
research Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin
Progerin affects cell shape but not hair or skin in mice.
research Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway
Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.
research c-Kit - The Novel Receptor: Physiological Roles, Downstream Signaling and Implications in Cancer
c-Kit is important for heart regeneration and cancer development.
research Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Organ regeneration based on developmental biology: past and future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites
Human skin cells can create new hair follicles when transplanted into mice.
research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2
MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
research Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours
Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
research Mesenchymal stem cells in periodontics: new perspectives
Tooth-derived stem cells show promise for regenerating gum tissue but need standardized selection methods.
research Mitogen‐regulated protein/proliferin mRNA induction following single applications of tumor promoters to murine skin
mrp/plf-mRNA can indicate tumor-promoting effects in skin.
research The long road traveled in hematopoietic stem cell gene therapy
The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
research Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1
Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
research Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors
Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
research 11 Plasma-Rich Protein and ACell
PRP is a promising, cost-effective treatment for hair loss by stimulating hair growth.
research Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders
Pluripotent stem cells show promise for treating skin color loss disorders like vitiligo.