26 citations
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October 2014 in “Andrologia” Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.
6 citations
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September 1997 in “Prostate Cancer and Prostatic Diseases” Finasteride 5 mg effectively reduces urinary symptoms and PSA levels in men with enlarged prostates, with few sexual side effects.
January 2025 in “Journal of Men s Health” Young men's erectile dysfunction is linked to mental health issues and risky behaviors promoted by online communities, highlighting the need for better mental health support and healthy masculinity standards.
77 citations
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October 2007 in “International Journal of Andrology” Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.
8 citations
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May 1982 in “Journal of Endocrinology/Journal of endocrinology” Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
39 citations
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November 2021 in “Clinical Endocrinology” Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
June 2022 in “Journal of Experimental Biology and Agricultural Sciences” Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.
19 citations
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March 2010 in “Bioorganic & Medicinal Chemistry Letters” Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
10 citations
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May 2021 in “Psychoneuroendocrinology” Testosterone levels aren't important for depression in men, but some other hormones might affect certain symptoms.
70 citations
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April 2014 in “Annales d'endocrinologie” New genes and pathways are important for testosterone production and male sexual development.
74 citations
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November 1975 in “Archives of dermatology” Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.
February 2005 in “The Journal of Urology” Finasteride for hair loss doesn't harm erectile function; weight loss and exercise improve it.
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August 2012 in “The Journal of Urology” Women with congenital adrenal hyperplasia showed no prostatic growth.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
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September 2013 in “Fertility and Sterility” Finasteride discontinuation increases sperm count in men.
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June 2022 in “Transgender Health” Oocyte retrieval is possible for transgender men on testosterone therapy without affecting fertility outcomes.
14 citations
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August 1997 in “The Journal of Urology” Finasteride can cause enlarged breasts.
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April 1997 in “Fertility and sterility” Clomiphene citrate can reverse low hormone levels and symptoms in male runners with hypogonadotropic hypogonadism.
133 citations
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August 1969 in “Science” Melatonin causes weasels to grow white fur and become reproductively inactive.
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January 1994 in “Journal of Society of Cosmetic Chemists of Japan” Hair grows slower and thinner with age, but a test tonic improved growth in alopecia subjects.
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October 2020 in “Microscopy and Microanalysis” Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.
17 citations
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January 2013 in “Our Dermatology Online” Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.
6 citations
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January 2010 in “Case Reports” A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.
March 2026 in “JCEM Case Reports” Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.
223 citations
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
June 2025 in “Reports of Vinnytsia National Medical University” Men with alopecia areata tend to have larger limb and trunk circumferences than healthy men.
105 citations
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June 2010 in “The journal of sexual medicine” Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.
20 citations
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June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
August 1987 in “European journal of endocrinology” The T/SHBG ratio may be a useful marker for androgen activity in women with androgenetic alopecia.
1 citations
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July 2017 in “The Journal of Urology” Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.