research Ausgeprägte Virilisierung in der Postmenopause - eine Falldarstellung
A postmenopausal woman had high testosterone from her right adrenal gland, leading to recommended surgery.
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research Intracrine testosterone activation in human pancreatic β cells stimulates insulin secretion.
Testosterone in human pancreas cells boosts insulin production.
research A Case of Hidradenitis Suppurativa Responsive to Testosterone Replacement Therapy
Testosterone therapy significantly improved Hidradenitis Suppurativa symptoms.
research A rare case of Cushing syndrome with virilization
A 10-year-old girl's symptoms improved after surgery to remove a benign adrenal tumor.
research Precocious Puberty
Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.
research Older age and low testosterone levels are independently associated with kidney stone prevalence in men: results from a large cross-sectional study
Older age and low testosterone increase the risk of kidney stones in men.
research Testosterone levels in healthy men and the relation to behavioural and physical characteristics: facts and constructs
Testosterone levels influence male behaviors and physical traits, but this relationship is complex and influenced by both internal and external factors.
research Myocyte Androgen Receptor Modulates Body Composition and Metabolic Parameters
Activating androgen receptors in muscle can increase muscle mass and reduce fat.
research Changes in the sebaceous gland in patients with male pattern hair loss (androgenic alopecia)
Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
research Investigation, treatment and monitoring of late‐onset hypogonadism in males: ISA, ISSAM, and EAU recommendations
Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
research In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research What is your diagnosis?
The woman likely has a hormonal imbalance causing excessive hair growth.
research 6450 Leydig Cell Tumor: A Rare Cause of Post-menopausal Hyperandrogenism
Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
research Truman Plus Male Enhancement [Get 100% Genuine Result] Achieve Bigger | Harder Erections(REAL OR HOAX)
Truman Plus Male Enhancement may help boost testosterone and improve sexual health, but severe cases need medical treatment.
research Ectopic hair on the glans penis
A man grew hair on his penis, which is not common, and needed surgery to remove it.
research News & Notes
Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
research Is age at puberty associated with semen quality and reproductive hormones in young adult life?
Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.
research Cytologic Atypia in a 53-Year-Old Man With Finasteride-Induced Gynecomastia
research Factors Driving Unique Urination Phenotypes of Male and Female 9-week-old C57BL/6J Mice
Testosterone significantly affects urination differences between male and female mice.
research External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
research This Month in Clinical Urology
New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.
research Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5α-Reductase: Definition of a Selective Role for Dihydrotestosterone*
Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
research Visual Vignette
The woman's symptoms and tests suggest her adrenal glands are producing too many male hormones.
research Menopausal Androgen Excess - Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumour (Case Report and Mini-Review of Literature)
High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
research Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines
Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
research Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone
Testosterone therapy increases bone density in older men with low testosterone levels.
research Morphometric-stereological and functional epididymal alterations and a decrease in fertility in rats treated with finasteride and after a 30-day post-treatment recovery period
Finasteride causes lasting fertility decrease in rats.
research Glatze in jungen Jahren könnte Risikofaktor für BPH sein
Early balding may be a sign of future prostate problems.