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A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

High doses of Lagenaria siceraria fruit powder lower FSH and LH hormone levels in male rats.

Finasteride causes reproductive changes in male rats.

Larger prostate size in older men may be linked to poorer semen quality and fertility issues.

PCS rats show significant inner ear damage and zinc deficiency, similar to liver cirrhosis patients.

A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

Gene mutations can cause problems in male genital development.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

New genes and pathways are important for testosterone production and male sexual development.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

Estrogens and androgens are crucial for male fertility.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.

Chromosomal differences affect how muscle cells respond to testosterone.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

A rare gene variant causes sexual development issues in siblings, needing personalized treatment.

Genetics may play a significant role in gender dysphoria.

Testosterone boosts fluid and electrolyte secretion in seminal vesicles, aiding sperm function.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.