research Effect of finasteride particle size reduction on its pharmacokinetic, tissue distribution and cellular permeation.
Smaller finasteride particles increase effectiveness in treating hair loss.
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research Androgens and hair: a biological paradox with clinical consequences
Androgens can both increase body hair and cause scalp hair loss.
research Proscar@ (Finasteride) inhibits 5α-reductase activity in the ovaries and testes of Lytechinus variegatus Lamarck (Echinodermata: Echinoidea)
Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
research Treatment of hyperandrogenism in women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Effects of Flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat
Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
research In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research Meta-Analysis on the Efficacy and Safety of Traditional Chinese Medicine as Adjuvant Therapy for Refractory Androgenetic Alopecia
Chinese medicine may help hair growth and reduce hair loss in androgenetic alopecia.
research Development and evaluation of finasteride loaded ethosomes for targeting to the pilosebaceous unit
Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.
research Association between male pattern baldness and prostate disease: A meta-analysis
Men with male pattern baldness have a higher risk of aggressive prostate cancer and benign prostatic hyperplasia.
research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 9 Days in Normal Men With Experimental Hypogonadism
The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
research RECENT DEVELOPMENTS IN ALOPECIAS
Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
research Finasteride and Suicide: A Postmarketing Case Series
Finasteride may increase suicide risk; more research needed.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Hair Loss and the Applied Techniques for Identification of Novel Hair Growth Promoters for Hair Re-Growth
Many products for hair re-growth exist, but a perfect treatment without side effects has not yet been found.
research Pharmacokinetics of 2 Novel Formulations of Modified-Release Oral Testosterone Alone and With Finasteride in Normal Men With Experimental Hypogonadism
New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
research A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia
MorrF improves hair growth better than minoxidil alone.
research The Biomedical Role of Zinc in the Functioning of the Human Organism
Zinc is essential for many body functions and imbalances can lead to health problems.
research 5α-reductase inhibitors
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Anti-androgen therapy in dermatology: a review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results
5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
research Framework guidelines for the process of caring for the health of adolescent transgender (T) and non-binary (NB) people experiencing gender dysphoria — the position statement of the expert panel
Provide individualized, supportive care for transgender and non-binary adolescents to improve their well-being.
research The Effects of Ficus carica on Male and Female Reproductive Capabilities in Rats
Ficus carica extract improved fertility in rats and may help with certain health conditions.
research Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration
Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
research Effects of non-contingent cocaine on 3alpha-androstanediol. I. Disruption of male sexual behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
research 5-alpha Reductase inhibitors and risk of male breast cancer: a systematic review and meta-analysis
Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.
research ANDROGEN METABOLISM AS IT AFFECTS HAIR GROWTH IN ANDROGENETIC ALOPECIA
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
research Adrenoleukodystrophy: A Rare Case Report
Early diagnosis and genetic counseling are crucial for managing adrenoleukodystrophy.
research A genetically informed brain atlas for enhancing brain imaging genomics
GIANT improves brain imaging by using genetics to better map brain regions.
research DIETARY AND PHARMACO-THERAPY IN SKIN DISEASES
Certain foods and supplements can help treat skin diseases alongside medication.