21 citations
,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
20 citations
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June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
19 citations
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January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
19 citations
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July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
17 citations
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May 1998 in “Steroids” Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
16 citations
,
January 2010 in “Drug Metabolism and Pharmacokinetics” Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
14 citations
,
January 2019 in “Journal of Natural Medicines” Chaga mushrooms contain compounds that may promote hair growth better than common treatments.
14 citations
,
November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
13 citations
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November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
11 citations
,
January 2015 in “Current problems in dermatology” The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.
11 citations
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May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
11 citations
,
November 2022 in “Journal of Endocrinological Investigation” Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
10 citations
,
November 2018 in “Physiological Research” The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
10 citations
,
May 2009 in “Sexual and Relationship Therapy” The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
9 citations
,
June 2002 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.
5 citations
,
August 2023 in “The World Journal of Men s Health” Red ginseng oil improves urinary symptoms and some sexual functions in men safely.
4 citations
,
May 2019 in “Physiology & Behavior” Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
3 citations
,
April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
1 citations
,
March 2021 in “Phytomedicine plus” Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
1 citations
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March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
April 2026 in “International Journal of Impotence Research” Anabolic steroid abuse can cause sexual, fertility, and health problems.
January 2026 in “Frontiers in Pharmacology” Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.
September 2025 in “Frontiers in Medicine” Angiopoietin-1 helps hair cells survive and grow, making it a potential treatment for hair loss.
August 2025 in “Research Square (Research Square)” High TNF-α levels may increase hair loss risk after PRP therapy.
January 2017 in “Clinical & medical biochemistry” Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
May 2013 in “Trends in Urology & Men's Health” Male-pattern hair loss is normal, often involves hormone effects on hair follicles, and can be treated with medication or surgery, but new treatments are being researched.
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
Modern hair restoration techniques can effectively treat hair loss and provide natural-looking results.