8 citations
,
March 2022 in “International Journal of Endocrinology” Combining spironolactone with metformin reduces insulin resistance in PCOS better than either drug alone.
8 citations
,
January 2012 in “General and Comparative Endocrinology” 5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.
8 citations
,
September 2005 in “Practical diabetes” PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.
5 citations
,
May 1994 in “Facial plastic surgery clinics of North America” Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
4 citations
,
December 2021 in “Pharmacological Reports” Metformin is less effective in men with early-onset hair loss.
4 citations
,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
2 citations
,
July 2021 in “Journal of Cardiovascular Pharmacology” Lisinopril improves heart health more in men with normal hair than those with early hair loss.
2 citations
,
July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Sex hormones likely don't affect atopic dermatitis in adolescents and adults.
2 citations
,
January 2020 in “Clinical Dermatology Review” Idiopathic hirsutism is the most common cause of hirsutism in women, followed by PCOS.
1 citations
,
December 2023 in “Diagnostics” Accurate testosterone measurement and standardized lab practices are crucial for diagnosing and managing adult male hypogonadism.
1 citations
,
August 2019 in “Journal of pediatric & adolescent gynecology” A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
1 citations
,
July 2006 in “Acta obstetricia et gynecologica Scandinavica” Physical activity significantly improved symptoms of PCOS in a patient.
May 2025 in “Clinical Endocrinology” Metformin lowers prolactin in men with normal hair but not in those with early hair loss.
April 2025 in “Journal of the International Society of Sports Nutrition” Creatine does not cause hair loss.
February 2025 in “Pharmaceuticals” Myo-inositol with magnesium effectively reduces acne and hirsutism in PCOS patients without side effects.
October 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Rodent models of PCOS show some similar and some different lipid changes compared to humans.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” Biotin can interfere with lab tests, causing misdiagnosis.
June 2024 in “Journal of Education, Health and Sport” Androgenetic alopecia can be treated with minoxidil and finasteride, requiring long-term use and patient cooperation.
October 2023 in “Journal of Preventive Diagnostic and Treatment Strategies in Medicine” Low ferritin and Vitamin D levels may cause hair loss after COVID-19.
September 2023 in “Cureus” Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
October 2022 in “The Egyptian Journal of Hospital Medicine” Females with idiopathic hirsutism have higher levels of omentin-1, which may lead to excessive hair growth.
The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
December 2023 in “Palestinian medical and pharmaceutical journal/Palestinian medical & pharmaceutical journal” Increasing sleep by 41 minutes daily for a month showed no significant changes in metabolism or hormone levels in healthy women.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.
May 2022 in “The Journal of Clinical Pharmacology” Metformin reduces certain hormone levels in men with early-onset hair loss.
37 citations
,
May 2018 in “Transgender health” Oral estradiol works for many transgender women but needs personalized dosing and monitoring.
1 citations
,
January 2022 in “BMC Genomic Data” The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.
175 citations
,
January 2020 in “European Journal of Endocrinology” Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
90 citations
,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
74 citations
,
January 2011 in “Reproductive Biology and Endocrinology” Testosterone therapy can improve hormone levels and quality of life in men with morphine-induced hormone issues.