82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
26 citations
,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.
59 citations
,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
21 citations
,
May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.
28 citations
,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
January 2024 in “Journal of cellular immunology” Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.
April 2026 in “International Journal of Molecular Sciences” Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
127 citations
,
March 2016 in “PLoS ONE” Key genes and pathways crucial for hair follicle development in cashmere goats were identified, aiding fleece production improvement.
October 2022 in “International Journal of Molecular Sciences” Fish collagen peptides can significantly promote hair growth.
176 citations
,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
19 citations
,
December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
18 citations
,
December 2020 in “Frontiers in cell and developmental biology” miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.
149 citations
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July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
18 citations
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April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
165 citations
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December 2004 in “Differentiation” BMP signaling is crucial for skin and hair growth.
28 citations
,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
1 citations
,
May 2024 in “Preprints.org” Rex rabbit fur is best harvested at 120 days for optimal hair density and quality.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
488 citations
,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
December 2025 in “Animals” TGFBR1 slows down cell growth in fine-wool sheep hair follicles.
April 2024 in “Biomedicine & pharmacotherapy” Pilose antler extract helps hair grow in mice with a type of hair loss by speeding up the growth phase.
June 2026 in “Frontiers in Cell and Developmental Biology” MicroRNAs can help regenerate hair by influencing stem cells and immune responses, but delivery challenges exist.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
245 citations
,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
January 2025 in “Cell Communication and Signaling” CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.
May 2024 in “Molecules/Molecules online/Molecules annual” Plant extracts can help prevent hair loss and promote hair growth.