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Nature-Derived Lignan Compound VB-1 Exerts Hair Growth-Promoting Effects by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells

research Peer Review #2 of "Nature-derived lignan compound VB-1 exerts hair growth-promoting effects by augmenting Wnt/β-catenin signaling in human dermal papilla cells (v0.1)"

May 2018

A natural compound called VB-1 can help promote hair growth by boosting a specific cell signal in human skin cells.

research Collagen and Fractionated Platelet-Rich Plasma Scaffold for Dermal Regeneration

42 citations , April 2016 in “Plastic and reconstructive surgery/PSEF CD journals”

The hydrogel with fractionated PRP improves skin regeneration by enhancing wound healing and growth of skin structures.

research MOESM1 of A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse

January 2017

research HDAC1-Overexpressing Dermal Papilla Cell-Derived Extracellular Vesicles Modulate p53 and Wnt/β-Catenin Signaling to Rescue Hair Follicle Regeneration in Androgenetic Alopecia

January 2026 in “Biomaterials”

research Bone marrow-derived vasculogenesis leads to scarless regeneration in deep wounds with periosteal defects

2 citations , November 2022 in “Scientific reports”

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

research Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein

16 citations , June 1992 in “Journal of Investigative Dermatology”

research Multiple potential roles of thymosin β4 in the growth and development of hair follicles

13 citations , January 2021 in “Journal of Cellular and Molecular Medicine”

Thymosin β4 may boost hair growth by aiding stem cell movement and blood vessel formation.

research Chitinase 3-Like 1 and C-X-C motif chemokine ligand 5 proteins and the hair cycle

August 2024 in “Archives of Dermatological Research”

CHI3L1 and CXCL5 proteins help promote hair growth.

research PLAU and SerpinB2 role in apoptosis in leprosy

May 2017 in “Journal of The American Academy of Dermatology”

PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.

research Proteoglycans and Associated Proteins of the Mammalian Hair Follicle

7 citations , May 1995 in “The journal of investigative dermatology/Journal of investigative dermatology”

research SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism

50 citations , November 2021 in “Viruses”

Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.

Thyrotropin-Releasing Hormone Promotes Wound Re-Epithelialisation in Frog and Human Skin

research Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin

46 citations , September 2013 in “PLOS ONE”

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

research Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in theArabidopsisRoot

84 citations , June 2010 in “The Plant Cell”

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

research Trichothiodystrophy with Dysmyelination and Central Osteosclerosis

16 citations , January 2010 in “American Journal of Neuroradiology”

Specific brain and bone imaging findings can help diagnose Trichothiodystrophy.

research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21

37 citations , January 1993 in “Journal of Investigative Dermatology”

research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture

38 citations , March 1997 in “Journal of interferon & cytokine research”

IL-1β inhibits human hair follicle growth.

research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation

9 citations , June 2016 in “Stem cells”

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

research Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration

25 citations , January 2013 in “Journal of Cell Science”

Tenascin-C and tenascin-W help control stem cell movement and growth in whisker follicles.

research Matriptase: Potent Proteolysis on the Cell Surface

165 citations , January 2006 in “Molecular Medicine”

Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.

research Does Vitamin D play a role on Msx1 homeoprotein expression involving an endogenous antisense mRNA?*1

May 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

Vitamin D affects Msx1 protein expression and may influence mineralized tissue health.

Serum Levels of VWF, t-PA, TNF-α, and ICAM-1 in Patients Receiving Hemocoagulase Combined with Platelet-Rich Plasma During Total Hip Replacement

research Serum Levels of VWF, t-PA, TNF-α, and ICAM-1 in Patients Receiving Hemocoagulase Combined with Platelet-Rich Plasma during Total Hip Replacement

2 citations , January 2022 in “Genetics Research”

Using hemocoagulase with platelet-rich plasma in hip replacement can lessen blood loss and improve healing and blood clotting.

research STEEL. IN: STRUCTURAL CONDITION ASSESSMENT

January 2005 in “Life sciences”

Targeting LPA could help treat skin disorders.

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