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November 2024 in “Frontiers in Immunology” Tertiary lymphoid structures are important in immunotherapy and need more research.
Dual TCR Treg cells are common in various mouse tissues and show diverse characteristics.
155 citations
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December 2002 in “Journal of Investigative Dermatology” Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
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February 2021 in “FEBS Journal” Targeting regulatory T cells may help treat age-related diseases.
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May 2012 in “Experimental Dermatology” July 2025 in “Journal of Investigative Dermatology” Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.
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July 2005 in “Journal of Investigative Dermatology” Sca-1+ cells in newborn mouse skin may become fat cells.
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November 2021 in “Protein and Peptide Letters” β-thymosin in invertebrates is more complex and diverse than in vertebrates.
January 2012 in “heiDOK (Heidelberg University)” Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.
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September 2024 in “Development” Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.
November 2020 in “International journal of contemporary pediatrics” Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
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June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
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March 2018 in “Experimental Dermatology” Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.
December 2021 in “Signal transduction and targeted therapy” Increasing sebum production might help reduce fat and improve metabolism.
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June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
Thymosin β4 helps heal corneal wounds.
November 2025 in “The Journal of Immunology” Different γδ T cell types have unique roles in causing alopecia areata.
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May 2025 in “The Journal of Dermatology” Increased regulatory T cell activity may lead to better outcomes in acute diffuse and total alopecia.
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June 2017 in “Nature Reviews Immunology” Immune cells called Treg cells are essential for hair growth and regeneration.
December 2014 in “Journal of Biomedical Research” Recombinant thymosin β4 promotes blood vessel growth and reduces muscle damage.
September 2025 in “Immunological Reviews” The skin can independently form immune responses through special structures, offering new ways to treat skin diseases.
April 2021 in “Journal of Investigative Dermatology” People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.
July 2024 in “Journal of Investigative Dermatology” CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.
November 2025 in “The Journal of Immunology” BST2 is highly expressed in certain immune cells in alopecia areata, suggesting a role in the disease.
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October 2022 in “International Journal of Molecular Sciences” Thy-1 protein helps improve blood flow and wound healing in the skin.
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
September 2016 in “Journal of Dermatological Science” Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.
245 citations
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October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
August 2019 in “Journal of Invertebrate Pathology” Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.
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September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.