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research Latent transforming growth factor beta-binding protein 1 (LTBP1): roles as a multifunctional extracellular matrix regulator in human disease. From molecular mechanisms to clinical translation prospects

March 2026 in “Folia Histochemica et Cytobiologica”

LTBP1 is a key regulator in diseases and a potential target for new treatments.

research Trichothiodystrophy with Dysmyelination and Central Osteosclerosis

16 citations , January 2010 in “American Journal of Neuroradiology”

Specific brain and bone imaging findings can help diagnose Trichothiodystrophy.

research TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs

September 2025 in “Stem Cell Research & Therapy”

TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.

research Sequences and differential expression of three novel human type-II hair keratins

61 citations , February 1997 in “Differentiation”

Hair differentiation starts earlier than thought, involving multiple type-II keratins.

research Transcriptional profiling of putative human epithelial stem cells

16 citations , July 2008 in “BMC Genomics”

Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.

research Identification and dissection of an enhancer controlling epithelial gene expression in skin

29 citations , February 2001 in “Proceedings of the National Academy of Sciences”

A specific DNA region controls skin cell gene expression by working with certain proteins.

research Decision letter: Structural basis of malodour precursor transport in the human axilla

March 2018

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

research Novel association of trichothiodystrophy with autoimmune thyroiditis and autoimmune hemolytic anemia: A case report

January 2023 in “Indian dermatology online journal”

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

research Somatotropin Penetration Testing from Formulations Applied Topically to the Skin

1 citations , February 2023 in “Applied sciences”

The new topical growth hormone formula has high skin penetration and bioavailability.

research Reversal of alopecia areata, osteoporosis follow treatment with activation of Tgr5 in mice

14 citations , July 2021 in “Bioscience Reports”

Activating Tgr5 may help treat hair loss and bone loss.

research A Novel Gene Homologous to Teashirt is Differentially Expressed in Neonatal Mouse Skin During Development of Hair Follicles

January 2004 in “Molecular biotechnology”

research YAP and TAZ are essential for basal and squamous cell carcinoma initiation

76 citations , June 2018 in “EMBO Reports”

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

research Anticytokine therapy, particularly anti-IFN-γ, in Th1-mediated autoimmune diseases

9 citations , May 2005 in “Expert Review of Clinical Immunology”

Blocking interferon-gamma might help treat various autoimmune diseases.

research Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine

24 citations , October 2019 in “Genes”

A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.

research FOXP3 ⁺ regulatory T cells and age‐related diseases

26 citations , February 2021 in “FEBS Journal”

Targeting regulatory T cells may help treat age-related diseases.

research Structural features and sites of expression of a new murine 65 kD and 48 kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation

28 citations , August 1992 in “Differentiation”

A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.

TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis

research TGF‐β₂ is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis

43 citations , March 2009 in “Journal of Cellular and Molecular Medicine”

TGF-β2 plays a key role in human hair growth and development.

research H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development

1 citations , August 2025 in “Epigenetics & Chromatin”

H3K4me3 helps control RSPO3 to influence hair growth and development.

research A case of monilethrix caused by novel compound heterozygous mutations in the desmoglein 4 (DSG4) gene

26 citations , April 2011 in “British Journal of Dermatology”

New mutations in the DSG4 gene cause a rare hair condition.

research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice

15 citations , May 2014 in “Journal of Biological Chemistry”

A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.

research Serum Plasma Thiol Evaluation in Chronic Telogen Effluvium Patients

June 2023 in “Benha Journal of Applied Sciences”

People with chronic hair shedding have lower antioxidant levels in their blood compared to healthy individuals.

research Distribution of human B-defensin 2, TNF-alpha, IL-1 alpha, IL-6 and IL-8 in psoriatic skin

1 citations , December 2012 in “Papers on Anthropology”

Certain proteins and cytokines are key in causing psoriatic skin issues.

research 42863 The association of milia-like calcinosis cutis, alopecia totalis and hyperthyroidism linked with the novel mutation for RBM28

September 2023 in “Journal of the American Academy of Dermatology”

Children with alopecia areata, especially with Down syndrome or thyroid issues, should be screened for thyroid disease.

research Parathyroid Hormone-related Protein in Normal and Neoplastic Canine Tissues: Immunohistochemical Localization and Biochemical Extraction

54 citations , May 1994 in “Veterinary Pathology”

PTHrP is higher in certain dog tumors and may act as a local growth factor.

research Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle

46 citations , November 1998 in “Experimental Cell Research”

K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.

research Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease

5 citations , February 2019 in “PloS one”

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

research GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis

24 citations , December 2013 in “Archives of Dermatological Research”

research Case report of Schöpf–Schulz–Passarge syndrome resulting from a missense mutation, p.Arg104Cys, in WNT10A

5 citations , December 2017 in “The Journal of Dermatology”

A new gene mutation caused a man's rare skin condition, Schöpf-Schulz-Passarge syndrome.

research The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity

55 citations , November 2010 in “Journal of Allergy and Clinical Immunology”

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

Cryo-EM and Molecular Dynamics of TRPV3 Channel in Activated State Reveal Structural Features Implicated in Severe Itch and Hyperkeratosis

research 738 Cryo-EM and molecular dynamics of TRPV3 channel in activated state reveal structural features implicated in severe itch and hyperkeratosis

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

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