August 2023 in “International journal of medical science and clinical research studies” PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
January 2023 in “Advanced Biology” DNA methylation changes affect gene expression during esophageal healing with silk grafts in rats.
November 2021 in “International Journal for Research in Applied Science and Engineering Technology” Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.
April 2018 in “Journal of Investigative Dermatology” Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
August 2016 in “Journal of Investigative Dermatology” Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.
November 2015 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” Platelet concentrates may help tissue regeneration and have potential for regenerative therapies.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
156 citations
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March 2022 in “Exploration” Bioactive inorganic particles-based biomaterials show promise for improving skin wound healing.
124 citations
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December 1983 in “Developmental Biology” EGF receptors are crucial for skin cell growth and decrease with age.
48 citations
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February 2010 in “Molecular biology reports” KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.
30 citations
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December 2017 in “Medical Hypotheses” The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
16 citations
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November 1994 in “Developmental Biology” Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.
15 citations
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April 2011 in “Biological Chemistry” Cathepsin E is crucial for normal skin cell differentiation and development.
9 citations
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December 2024 in “Nano Research” A protein-based hydrogel helps heal diabetic wounds and repair nerves.
8 citations
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June 2001 in “Journal of Biological Chemistry” A truncated protein linked to breast cancer may change cell adhesion.
6 citations
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July 2021 in “Microbial biotechnology” The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.
1 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” Regenerative medicine shows promise for aesthetic surgery, but needs more research for widespread use.
December 2009 in “생명과학회지” Thymosin β4 and VEGF are important for organ function and may help with blood vessel formation.
113 citations
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June 2010 in “Biological Chemistry” Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.
13 citations
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February 2010 in “Stem Cell Reviews and Reports” Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
8 citations
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June 2022 in “Frontiers in bioengineering and biotechnology” A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
1 citations
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November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
October 2025 in “Journal of Translational Medicine” Combining biomaterials and cell pathways can improve hair follicle regeneration.
1039 citations
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February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
773 citations
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August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
658 citations
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
479 citations
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June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.