October 2024 in “Acta Biomaterialia” Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
Careful diagnosis and management of MCTD are crucial due to potential severe complications.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
June 2014 in “Biotechnology and Bioprocess Engineering” Injecting lab-grown hair cells into the scalp can regrow hair.
288 citations
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January 2001 in “Journal of Biological Chemistry” Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.
136 citations
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September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
82 citations
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May 2020 in “International Journal of Molecular Sciences” Injectable biomaterials can effectively regenerate dental tissues.
41 citations
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May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
20 citations
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May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
18 citations
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May 2017 in “Experimental Dermatology” AMT may cause hair loss and changing dWAT activity could help treat it.
14 citations
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August 2018 in “Frontiers in Cellular and Infection Microbiology” Dengue virus can infect human hair follicle cells and may cause hair loss.
9 citations
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December 2021 in “Journal of Cellular and Molecular Medicine” HAT-MSCs can effectively engulf harmful microbes and particles, aiding infection treatment.
8 citations
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May 2023 in “Gels” Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
Removing SIX1 in fat cells reduces skin fibrosis.
September 2023 in “Cureus” Nails can reveal important health information about skin and body conditions.
September 2023 in “The FASEB journal” Foxn1 is important for fat development, metabolism, and wound healing in skin.
August 2023 in “MOJ women's health” Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
April 2019 in “Journal of Investigative Dermatology” Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
124 citations
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July 1997 in “Journal of Biological Chemistry” Overexpressing a specific enzyme in mice causes hair loss and female infertility.
28 citations
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March 2019 in “Cellular Microbiology” Intravital microscopy helps us see how parasites interact with skin and fat in living animals.
12 citations
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September 2022 in “Frontiers in Genetics” Enhancing CD8+ T cell function to induce ferroptosis in tumor cells may help treat skin melanoma.
1 citations
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March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
49 citations
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January 2023 in “Gels” Hydrogels are crucial for 3D bioprinting in tissue engineering.
14 citations
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November 2022 in “Development” Controlling transposable elements is crucial for successful tissue regeneration.
11 citations
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September 2023 in “ACS Omega” 3D bioprinting is advancing rapidly, improving regenerative therapy and drug delivery.