research Surgical Pearl: Mechanoanesthesia to reduce the pain of local injections
Using a vibrating device during injections can help reduce pain.
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360-390 / 1000+ results research Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized trial
Combining microneedling with either vitamin D3 or bimatoprost improves hair regrowth more than microneedling alone.
research Microneedle mediated transdermal delivery of β-sitosterol loaded nanostructured lipid nanoparticles for androgenic alopecia
The microneedle system effectively promotes hair growth for treating androgenic alopecia.
research Biological properties of polycaprolactone and barium titanate composite in biomedical applications
Polycaprolactone and barium titanate composites show promise for use in biomedical applications.
research Poly (lactic-co-glycolic acid)-based microneedles for drug delivery across different biological barriers
PLGA-based microneedles show promise for painless, long-term drug delivery but need design and safety improvements.
research Sticking It to Alopecia
Triamcinolone acetonide injections help regrow hair in alopecia areata patients.
research Platelet-rich plasma for androgenetic alopecia: intradermal injection or microneedle delivery?
Microneedle delivery of platelet-rich plasma may be slightly better for hair regrowth than intradermal injection.
research Microneedle‐Assisted Delivery of PEGylated Recombinant Human Fusion Collagen for Androgenetic Alopecia: Preclinical and Pilot Clinical Evidence
Microneedle delivery of a special collagen shows promise for treating hair loss.
research Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo
Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
research Contouring of the Forehead Irregularities (Washboard Effect) With Bone Biomaterial
Cerament effectively corrected forehead irregularities in one patient, and various surgical techniques successfully reconstructed perioral soft tissue in 14 patients.
research Comparison of tissue loss by different punches: A new A‐design
The new A-design punch for hair restoration surgery may lead to smaller scars compared to other types.
research The effects of fulvic acids and low-level laser therapy on orthodontic retention in rats
Low-level laser therapy reduces orthodontic relapse in rats, but fulvic acids do not.
research 54440 An open label trial evaluating the use of microneedling in hair loss
Microneedling mildly regrows hair in androgenetic alopecia but not in other types.
research Dissolving microneedles incorporating kopexil multicomponent crystals for improved transdermal delivery
Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.
research Evaluation of polyamide synthetic hair. A long-term clinical study.
The study found that using polyamide synthetic hair for implants is generally safe and gives good results with proper medical follow-up.
research Intralesional Pentoxifylline Injection Versus Triamcinolone Acetonide in Treating localized Alopecia Areata: A Comparative Study.
Pentoxifylline is a safe and effective alternative to triamcinolone acetonide for treating localized alopecia areata.
research FCP 8 : Effect on hair growth using microneedle devices in hairless mouse
A 0.5 mm microneedle roller best promotes hair growth.
research 10 Complications Associated with PRP and Microneedling in Aesthetic Medicine
Microneedling and PRP are generally safe but can cause mild skin issues; serious problems are rare.
research Dexmedetomidine-Loaded Hydrogel Microneedles Alleviate Acute Inflammatory Visceral Pain in Mice
The study introduces a novel approach for treating acute inflammatory visceral pain (AIVP) using dexmedetomidine-loaded hyaluronic acid hydrogel microneedles (MN/Dex). This method offers a minimally invasive, patient-friendly alternative to traditional intravenous administration, which can be uncomfortable and pose infection risks. The microneedles enable efficient skin penetration and controlled drug release, demonstrating excellent biocompatibility in biosafety evaluations. In a mouse model of AIVP, MN/Dex significantly reduced pain without causing sedation or affecting normal behaviors, suggesting its potential to improve outpatient management and quality of life for patients with AIVP.
research Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides
Polynucleotide injections improved eye wrinkles with few side effects.
research Microneedling for Cutaneous Manifestations of Autoimmune Disease: A Scoping Review
Microneedling may help treat some autoimmune skin conditions, but more research is needed.
research When Microneedling Backfires: A Hidden Risk of Hair Shaft Fragility in AGA Patients
Microneedling can weaken hair in some AGA patients.
research The Applications of Medical Tattooing in the Head and Neck Region
Medical tattooing improves appearance and quality of life, but has potential risks.
research The Effect of Microneedling on Skin Histology: Review of Literature
Microneedling safely improves skin by boosting collagen and elastin, helping with scars, stretch marks, and other skin issues.
research FEMALE CADAVER IN THE HAN TOMB NO. 1 X-RAY DIFFRACTION STUDIES ON TWO KINDS OF FIBROUS PROTEIN
The protein structures in the hair and tendon were preserved, but their molecular arrangements changed.
research Novel tip-loaded dissolving and implantable microneedle array patches for sustained release of finasteride
New dissolving and implantable microneedle patches have been created for a long-lasting, non-invasive delivery of the drug finasteride.
research Orders & Contracts
The method effectively delivers vaccines through the skin without needles.
research How much medication is delivered in a novel drug delivery technique that uses a tattoo machine?
The tattoo machine method safely delivers an average of 1,175 µg/cm² of medication into the skin.
research P.08: Development of dissolving microneedles containing finasteride with improved permeability and bioavailability.
Dissolving microneedles with finasteride improve drug delivery for hair loss treatment.
research Promotion of Hair Regrowth by Transdermal Dissolvable Microneedles Loaded with Rapamycin and Epigallocatechin Gallate Nanoparticles
The microneedle device with rapamycin and epigallocatechin gallate effectively promoted hair regrowth in mice.