14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
59 citations
,
July 2020 in “Journal of The American Academy of Dermatology” Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.
51 citations
,
October 2024 in “Pharmaceutics” Improving drug delivery through the skin requires understanding skin and using enhancers.
23 citations
,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
21 citations
,
May 2016 in “The Cochrane library” Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
10 citations
,
February 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that proper diagnosis and evidence-based treatments are crucial for managing hair diseases, and psychological support for patients is important.
9 citations
,
January 2018 in “Journal of the European Academy of Dermatology and Venereology” A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
4 citations
,
July 2021 in “Dermatology and therapy” Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.
3 citations
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January 2020 in “Skin appendage disorders” In Spain, dermatologists most commonly prescribe topical minoxidil and oral finasteride for male hair loss, and topical minoxidil and oral contraceptives for female hair loss. The use of oral dutasteride and oral minoxidil has significantly increased over the past three years.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” Androgenetic alopecia treatments are becoming more personalized and include new therapies like topical antiandrogens and regenerative strategies.
Alopesi tedavisinde ilaçlar saç büyümesini teşvik eder ve yeni yaklaşımlar umut vaat eder.
April 2025 in “European Journal of Pharmaceutics and Biopharmaceutics” The new drug delivery system improves bicalutamide skin retention for better treatment of hair loss.
January 2025 in “Journal of the American Academy of Dermatology” Combining oral minoxidil and bicalutamide may help improve hair growth in adolescent girls.
January 2025 in “JAAD International” Bicalutamide added no extra benefit over minoxidil alone for female-pattern hair loss.
September 2024 in “Indian Journal of Dermatology Venereology and Leprology” Mesotherapy with bicalutamide has limited effectiveness for female hair loss.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.
January 2022 in “Turk Dermatoloji Dergisi” Topical procyanidin B2 significantly increases hair count and is a safe treatment for male pattern baldness.
November 2025 in “Open Repository of the University of Porto (University of Porto)” Continuous use of finasteride and minoxidil is effective for treating androgenetic alopecia.
March 2025 in “JAAD reviews.” Bicalutamide can reduce female pattern hair loss, especially in those with certain conditions, but has limited effects on other hair loss types.
6 citations
,
July 2013 in “Acta Clinica Belgica” The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” Bicalutamide may help treat female pattern hair loss.
January 2023 in “International Journal of Trichology” Bicalutamide mesotherapy may help with hair loss and seborrhea but needs more research.
26 citations
,
October 2011 in “International Journal of Biological Macromolecules” Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
20 citations
,
March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
6 citations
,
August 2020 in “JCRPE” A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
February 2025 in “Expert Opinion on Drug Metabolism & Toxicology” Future alopecia treatments will improve with targeted therapies and personalized approaches.
17 citations
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November 2021 in “Journal of Cosmetic Dermatology” Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.
16 citations
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August 2023 in “JAAD Case Reports” JAK inhibitors, like ruxolitinib, may effectively treat frontal fibrosing alopecia.
5 citations
,
May 2020 in “Journal of the American Academy of Dermatology” AGA might indicate higher risk for severe COVID-19.