9 citations
,
January 1992 in “Contact Dermatitis” Some people using minoxidil for hair loss developed an allergic skin reaction, often related to an ingredient that helps minoxidil work better.
3 citations
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September 2018 in “Current Drug Delivery” The combination of propylene glycol and Tween® 80 improves finasteride gel effectiveness.
A man got an allergic skin reaction after using a 5% minoxidil solution for hair growth, suggesting it's important to check the ingredients of such solutions.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
June 1992 in “Inpharma Weekly” Patch testing with different solvents helps find the right minoxidil formulation for those with scalp allergies.
September 1987 in “International Journal of Dermatology” Dr. Baral observed that applying minoxidil can cause hair to grow in areas other than where it was applied.
May 2023 in “International Journal of Trichology” A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.
March 2025 in “Molecules” Tectona grandis leaf extracts, especially with propylene glycol, may be promising for topical hair loss treatments.
11 citations
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July 2010 in “Dermatitis” Patch testing helps find allergens in minoxidil treatments, but doesn't ensure alternatives will be tolerated.
September 2010 in “Reactions Weekly” A woman was allergic to 5% minoxidil, with stronger reactions to higher concentrations.
A rash from semaglutide may be due to propylene glycol, not the drug itself.
June 2024 in “Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān.” Eucalyptus and Tween 80 most effectively increase cetirizine skin absorption.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.
Niosomes improve aminexil's effectiveness in preventing hair loss without needing propylene glycol.
Azelaic acid and vitamin B6 together may improve hair growth.
December 2022 in “Journal of Tropical Pharmacy and Chemistry” The hair tonic made from oil palm leaf extract is very effective in preventing hair damage from the sun.
January 2017 in “Nasza Dermatologia Online” Both treatments helped hair regrowth in alopecia areata, with isopropanol being better tolerated.
34 citations
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October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
1 citations
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March 2024 in “International Journal of Applied Pharmaceutics” Propylene glycol concentration improves rice water gel shampoo's thickness and foam, extending its shelf life.
7 citations
,
February 2019 in “Journal of Molecular Liquids” Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.
18 citations
,
March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
11 citations
,
January 2006 in “Drug development and industrial pharmacy” Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
58 citations
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December 2012 in “Aaps Pharmscitech” LCN may improve finasteride delivery for hair loss treatment.
October 2017 in “Our Dermatology Online” DCP in isopropanol is better tolerated for treating alopecia areata.
130 citations
,
January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
68 citations
,
March 2002 in “Journal of pharmaceutical sciences” Nonionic liposomes are the best for delivering genes to skin cells.
16 citations
,
December 2016 in “Skin appendage disorders” Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.
January 2024 in “Advances in health sciences research/Advances in Health Sciences Research” Sweet potato leaf extract can effectively treat dandruff.
55 citations
,
June 2009 in “Journal of Pharmaceutical Sciences” Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.
29 citations
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August 1985 in “Contact Dermatitis” Minoxidil can cause allergic reactions like burning, itching, and red bumps.