116 citations
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October 1982 in “The Journal of Pathology” Cyclosporin A is highly toxic to rats, causing severe health issues and death.
35 citations
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August 1978 in “Australian Veterinary Journal” Feeding steers only Leucaena leucocephala causes severe health issues and poor weight gain.
20 citations
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January 2019 in “Toxicology Reports” Dunaliella salina microalgae is safe to eat and may boost health.
15 citations
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July 2023 in “EClinicalMedicine” ADCs can effectively treat breast cancer but may cause side effects like nausea and hair loss.
13 citations
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July 1978 in “Journal of comparative pathology” Acanthospermum hispidum is toxic to mice, causing death and damage to internal organs.
12 citations
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June 2023 in “Journal of trace elements in medicine and biology” Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
5 citations
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January 2016 in “BLDE University Journal of Health Sciences” Kasisa Bhasma is safer and nontoxic compared to Shodhita Kasisa.
2 citations
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May 1985 in “Environmental Health Perspectives” Chlorinated compounds like TCDD can cause skin issues and chloracne by affecting cell behavior.
August 2025 in “Quality in Sport” Vitamin A is essential but too much can be harmful, especially from supplements.
June 2025 in “Journal of Cluster Science” Metal nanoparticles show promise for treating hair loss but need more research to ensure safety.
September 2023 in “Journal of pharmacognosy and phytochemistry” Plumbago zeylanica has valuable medicinal properties but needs sustainable cultivation methods.
December 2024 in “Jurnal Mandala Pharmacon Indonesia” Ramania leaf extract is non-toxic but can cause stomach ulcers at high doses.
August 2024 in “Bioimpacts” Kopexil is an effective and safe hair growth treatment.
July 2020 in “Environmental Science and Pollution Research” Finasteride harms invertebrates' survival and burial ability.
550 citations
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January 2012 in “Oxford University Research Archive (ORA) (University of Oxford)” Lithium can cause some health issues, but severe risks are low.
278 citations
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May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
116 citations
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May 1992 in “The American Journal of Medicine” Flutamide rarely causes liver toxicity in prostate cancer patients.
114 citations
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March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
104 citations
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January 2014 in “Journal of Clinical and Experimental Dentistry” This systematic review from 2014 examined the oral toxic effects of chemotherapy, highlighting its impact on both cancerous and rapidly multiplying normal cells, such as those in the oral mucosa. The study identified 333 relevant articles and found that chemotherapy could lead to complications like mucositis, osteonecrosis of the jaws, increased infection risk, dental alterations, salivary and neurological disorders, dysgeusia, and bleeding tendencies. These side effects significantly affected patients' quality of life and could be life-threatening. The review concluded that assessing patients' oral and dental health before chemotherapy was crucial to reducing the risk of these complications.
78 citations
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December 2011 in “Clinical toxicology” Excessive selenium from a supplement caused toxicity but patients recovered with care.
76 citations
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August 2007 in “Supportive care in cancer” Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
71 citations
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June 2008 in “Annals of Internal Medicine” Excessive selenium from supplements can be harmful.
54 citations
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March 1991 in “Proceedings of the National Academy of Sciences” This model can replace animal testing for quick, cost-effective skin toxicity tests.
32 citations
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May 2018 in “Journal of the American Academy of Dermatology” Skin reactions from cancer treatments might predict how well the treatments work.
27 citations
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June 2010 in “Journal of the American Academy of Dermatology” Excessive selenium in supplements can cause hair loss and nail issues.
25 citations
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May 2018 in “Clinical & Translational Oncology” New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
21 citations
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February 1988 in “Toxicology” High doses of TCB cause severe health issues in marmoset monkeys.
21 citations
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September 1966 in “Toxicology and Applied Pharmacology” Caffeine becomes more toxic in rats when food intake is reduced by over 50%.
20 citations
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September 2019 in “South African Journal of Botany” Teucrium polium extracts are non-toxic and effectively speed up wound healing.
19 citations
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October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.