research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
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research Region-specific reversal of epidermal planar polarity in the rosette fancy mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
research Role of the Wnt signaling pathway in keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response
AI improves biomaterial design by making it faster, cheaper, and more effective for personalized medicine.
research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research NOVEL CORONAVIRUS (SARS-COV-2): MOLECULAR BIOLOGY, PATHOGENESIS, PATHOBIOLOGY AND ADVANCES IN TREATMENT OF COVID-19 PATIENTS– AN UPDATE
COVID-19 is caused by a virus from bats, and efforts focus on prevention and treatment research.
research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of ‘Omics-Based Approaches
Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.
research Androgenetic Alopecia
Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
research Caracterização e diferenciação neural in vitro de células-tronco de polpa de dente decíduo humano
Dental pulp stem cells might not reliably become neurons.
research Skin aging: mechanisms, evaluation, and rejuvenation
Skin aging can be slowed by targeting cells, hormones, and the microbiome.
research Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism
Red light exposure can slow aging in mice by improving fat metabolism.
research A Comprehensive Survey on Vitiligo Detection Using Deep Learning
Better datasets and methods are needed for reliable vitiligo detection using deep learning.
research Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors
Genetics, epigenetics, and lifestyle all influence facial skin aging.
research Keeping up with the neighbours: local synchronisation of cell fate decisions during development
Cells communicate with neighbors to coordinate their development.
research Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS)
Hair follicles can be used to study gene expression and understand conditions like COPD.
research Transcriptome sequencing reveals the key genes associated with hair follicle development in Qianhua Mutton Merino
Key genes like KRT27 and IGF-2 are crucial for hair follicle development in Qianhua Mutton Merino sheep.
research Gentamicin-loaded exosomes from IMMUNEPOTENT CRP enhance healing of infected diabetic wound in mice
Gentamicin-loaded exosomes improve healing of infected diabetic wounds in mice.
research Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
research Somatic mutations distinguish melanocyte subpopulations in human skin
Hair follicles protect melanocytes from sun damage, helping them replenish skin.
research Research advances of tissue-derived extracellular vesicles in cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.
research Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea
Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.
research Genome scan for signatures of adaptive evolution in wild African goat (capra nubiana)
Wild African goats have genetic adaptations for surviving harsh desert conditions.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.
Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Cutaneous wound healing: recruiting developmental pathways for regeneration
Understanding developmental pathways can improve wound healing treatments.
research The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.