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Glossarytranscriptome

complete set of RNA molecules expressed in a cell

The transcriptome is the complete set of RNA molecules, including messenger RNA (mRNA), produced in a cell or a population of cells. It reflects the genes that are actively being expressed at any given time, providing insights into cellular function and regulation. For professionals, analyzing the transcriptome can reveal how cells respond to various conditions and can be crucial for understanding diseases like alopecia at a molecular level.

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research Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep

112 citations , September 2021 in “BMC Biology”

Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.

research Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus)

81 citations , September 2013 in “PLoS ONE”

Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.

research Analyses of histological and transcriptome differences in the skin of short-hair and long-hair rabbits

59 citations , February 2019 in “BMC Genomics”

Hair length in rabbits is linked to differences in lipid metabolism and cell death.

research Transcriptome Profile at Different Physiological Stages Reveals Potential Mode for Curly Fleece in Chinese Tan Sheep

55 citations , August 2013 in “PloS one”

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

research Transcriptomic analyses of regenerating adult feathers in chicken

45 citations , October 2015 in “BMC Genomics”

Chicken feather growth involves specific genes and shares similarities with hair development.

research Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin

37 citations , May 2018 in “Frontiers in physiology”

Certain RNA molecules are important for the development of wool follicles in sheep.

research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs

34 citations , August 2016 in “Scientific Reports”

Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.

Differential Gene Expression Analysis Between Anagen and Telogen of Capra Hircus Skin Based on the De Novo Assembled Transcriptome Sequence

research Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence

31 citations , March 2013 in “Gene”

Signaling pathways are crucial for hair growth in goats.

Comparative Transcriptome Analysis Reveals That a Ubiquitin-Mediated Proteolysis Pathway Is Important for Primary and Secondary Hair Follicle Development in Cashmere Goats

research Comparative Transcriptome Analysis Reveals that a Ubiquitin-Mediated Proteolysis Pathway Is Important for Primary and Secondary Hair Follicle Development in Cashmere Goats

31 citations , October 2016 in “PLoS ONE”

The ubiquitin-mediated proteolysis pathway is crucial for hair follicle development in cashmere goats.

research Transcriptomic analysis reveals critical genes for the hair follicle of Inner Mongolia cashmere goat from catagen to telogen

25 citations , October 2018 in “PloS one”

Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.

research Transcriptomic analysis of human skin wound healing and rejuvenation following ablative fractional laser treatment

24 citations , November 2021 in “PLoS ONE”

Ablative fractional laser treatment rejuvenates skin by altering gene expression and promoting wound healing and tissue regeneration.

research Transcriptome-based selection and validation of optimal house-keeping genes for skin research in goats (Capra hircus)

23 citations , July 2020 in “BMC Genomics”

NCBP3, SDHA, and PTPRA are the best genes for accurate goat skin research.

research Transcriptomic regulation of seasonal coat color change in hares

18 citations , January 2020 in “Ecology and evolution”

Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.

research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile

18 citations , April 2016 in “The journal of immunology/The Journal of immunology”

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.

research The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome

17 citations , March 2022 in “BMC Genomics”

Cashmere fiber diameter in Tibetan goats is influenced by their stress, oxygen, and metabolic adaptations.

research Transcriptome analysis reveals improved root hair growth in trifoliate orange seedlings by arbuscular mycorrhizal fungi

16 citations , May 2020 in “Plant Growth Regulation”

research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling

13 citations , September 2022 in “Biomolecules”

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging

research Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging

12 citations , June 2021 in “Scientific Reports”

Curcumin may help reverse aging by targeting specific genes.

Transcriptomic Inspection Revealed a Possible Pathway Regulating the Formation of the High-Quality Brush Hair in Chinese Haimen Goat (Capra Hircus)

research Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat ( Capra hircus )

11 citations , January 2018 in “Royal Society Open Science”

Scientists found genes linked to the growth of high-quality brush hair in Chinese Haimen goats.

research Transcriptome meta-analysis reveals the hair genetic rules in six animal breeds and genes associated with wool fineness

10 citations , June 2024 in “Frontiers in Genetics”

Different sheep breeds share similar genetic factors affecting wool fineness.

Transcriptome Sequencing and Identification of Cytochrome P450 Monooxygenases Involved in the Biosynthesis of Maslinic Acid and Corosolic Acid in Avicennia Marina

research Transcriptome sequencing and identification of cytochrome P450 monooxygenases involved in the biosynthesis of maslinic acid and corosolic acid in <i>Avicennia marina</i>

10 citations , October 2018 in “Plant Biotechnology”

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

research Human hair follicle transcriptome profiling: a minimally invasive tool to assess molecular adaptations upon low‐volume, high‐intensity interval training

10 citations , December 2017 in “Physiological Reports”

Hair follicle analysis can track body changes from high-intensity interval training.

research Transcriptome Analysis Reveals Skin Lipid Metabolism Related to Wool Diameter in Sheep

10 citations , May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)”

Lipid metabolism affects wool thickness in sheep.

research Evaluation of noninvasive biospecimens for transcriptome studies

9 citations , December 2023 in “BMC Genomics”

Hair follicles and urine cell pellets are promising for transcriptome studies.

research Transcriptome Profiling of Human Follicle Dermal Papilla Cells in response to Porphyra-334 Treatment by RNA-Seq

7 citations , January 2021 in “Evidence-based complementary and alternative medicine”

Porphyra-334 may help reduce wrinkles and promote hair growth.

research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis

7 citations , August 2020 in “Genes”

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

Transcriptome Analyses of Reprogrammed Feather/Scale Chimeric Explants Revealed Co-Expressed Epithelial Gene Networks During Organ Specification

research Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification

7 citations , October 2018 in “BMC genomics”

Key genes can rewire networks, changing skin appendage types.

research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology

7 citations , June 2024 in “Communications Medicine”

Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.

research Transcriptome profiling of whisker follicles in methamphetamine self-administered rats

6 citations , July 2018 in “Scientific Reports”

Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.

In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos

research In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos (Anser cygnoides)

6 citations , May 2022 in “Frontiers in physiology”

Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.