61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
September 2025 in “Pharmaceutics” Quercetin nanocrystal gel shows promise for hair regrowth in androgenetic alopecia.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
48 citations
,
January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
1 citations
,
April 2024 in “Journal of Drug Delivery Science and Technology” Microneedles combined with conventional therapies show promise in treating alopecia areata.
December 2025 in “Phytomedicine Plus” Combining herbal medicines with modern delivery systems may improve alopecia treatment.
21 citations
,
July 2015 in “International Journal of Nanomedicine” Increased liposome fluidity boosts skin penetration of sodium fluorescein.
37 citations
,
November 2024 in “Cosmetics” Ethosomes enhance skin penetration better than liposomes, benefiting therapeutic and cosmetic applications.
9 citations
,
March 2024 in “Journal of Biomaterials Applications” Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.
June 2024 in “International journal of nanomedicine” Azelaic acid micro/nanocrystals, especially with ultrasound and salicylic acid, greatly improve acne treatment.
2 citations
,
March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
43 citations
,
November 2012 in “Pharmaceutical research” Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
26 citations
,
July 2023 in “International Journal of Nanomedicine” The microneedle system shows promise for non-invasive brain drug delivery.
January 2025 in “Regenerative Biomaterials” A dissolving microneedle patch with collagen XVII effectively promotes hair regrowth in androgenic alopecia.
1 citations
,
November 2022 in “Pharmaceutical research” The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
42 citations
,
January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
33 citations
,
November 2019 in “Journal of Controlled Release” Microneedles with enhancer effectively promote hair growth and increase hair density.
29 citations
,
June 2014 in “Drug delivery” The new formulation improved the skin absorption of the drug Thiocolchicoside.
14 citations
,
January 2025 in “AAPS PharmSciTech” Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
15 citations
,
November 2017 in “Drug Delivery and Translational Research” Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.
30 citations
,
March 2016 in “European Journal of Pharmaceutical Sciences” Optimized film improves finasteride skin absorption and treatment efficiency.
January 2025 in “Journal of Pharmaceutical Research Science & Technology” Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.
34 citations
,
October 2021 in “Scientific Reports” Nobiletin-loaded vesicles effectively treat skin cancer by restoring normal miRNA and antioxidant levels.
26 citations
,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
19 citations
,
December 2013 in “European journal of pharmaceutics and biopharmaceutics” Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.
15 citations
,
May 2016 in “Die Pharmazie” Nanostructured lipid carriers deliver lidocaine to the skin better than nanoethosomes.
13 citations
,
August 2013 in “Journal of pharmaceutical sciences” Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
12 citations
,
June 2022 in “FARMACIA” Transethosomal gels improve naftifine skin delivery better than Exoderil cream.
9 citations
,
October 2013 in “Drug Delivery” Ethosomal carriers effectively deliver hair loss drug into skin.
3 citations
,
September 1989 in “Journal of Investigative Dermatology” Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.